# Enhancing Pediatric Treatment Adherence and Health Outcomes

> **NIH NIH T32** · CINCINNATI CHILDRENS HOSP MED CTR · 2021 · $272,367

## Abstract

PROJECT SUMMARY
 This proposal requests continued support for the “Enhancing Pediatric Treatment Adherence and Health
Outcomes” (T32 HD068223) postdoctoral training program, which trains M.D. and Ph.D. researchers to
assume leadership roles in developing innovative, high impact research on adherence to medical treatment
and chronic illness management that will enhance the health outcomes of children with chronic conditions.
Modern medical treatments have improved the health outcomes of large numbers of children and adolescents
with chronic conditions. However, one of the most critical remaining barriers to improving children's health
outcomes over the course of their lifetime is nonadherence to prescribed medical treatment. As noted by the
World Health Organization (WHO), treatment nonadherence is highly prevalent (rates of ≥ 50% in pediatric
chronic illness populations) and has a significantly negative impact on children's health and health care costs.
 Continued innovative and clinically relevant research is needed to close the gap between the health
outcomes that are potentially achievable with more optimal treatment adherence and those achieved in current
practice. NIH program priorities and requests for applications, scientific consensus conferences, and scholarly
reviews have all identified the critical importance of research on pediatric adherence to treatment. A critical
barrier to scientific advances in pediatric adherence and chronic illness management research is the shortage
of talented, well-trained researchers who are devoting their careers to developing innovative, high impact
treatment adherence and chronic illness management research with pediatric populations. One of the most
promising ways to address this need and improve child health is to develop innovative interdisciplinary
research training programs to train leaders in the field of treatment adherence and chronic illness management
research. This is the focus of this T32 program. Thus far, we have trained several fellows who are developing
promising independent research careers in pediatric adherence and chronic illness management.
 Specific training innovations involve the integration of biomedical, behavioral, biostatistics, and health
services/outcomes research and are reflected in a comprehensive training curriculum and research
opportunities. Research innovations include novel methods of adherence assessment and intervention
involving technology designed to enhance the engagement of children and adolescents, improve the power
and duration of intervention effects, and reach diverse populations who cannot easily access traditional clinic-
based approaches. Program innovation is also enhanced by novel research training opportunities to evaluate
the comparative effectiveness of adherence promotion interventions in pediatric chronic illness management,
to integrate objective methods of adherence measurement (e.g., behavioral, pharmacological, technological)
and conduct adva...

## Key facts

- **NIH application ID:** 10160937
- **Project number:** 5T32HD068223-10
- **Recipient organization:** CINCINNATI CHILDRENS HOSP MED CTR
- **Principal Investigator:** Kevin Hommel
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $272,367
- **Award type:** 5
- **Project period:** 2012-05-04 → 2022-09-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10160937

## Citation

> US National Institutes of Health, RePORTER application 10160937, Enhancing Pediatric Treatment Adherence and Health Outcomes (5T32HD068223-10). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10160937. Licensed CC0.

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