# Predoctoral Training Program in Human Genetics

> **NIH NIH T32** · JOHNS HOPKINS UNIVERSITY · 2021 · $355,008

## Abstract

PROJECT SUMMARY
 The Johns Hopkins Predoctoral Training Program in Human Genetics (HG) has grown
steadily since its inception in 1980 in parallel to the spectacular growth of genetics and
genomics and their application to medicine over the last four decades. Similarly, the Johns
Hopkins School of Medicine continues to make commitments to human genetics as
evidenced by the establishment of the McKusick-Nathans Institute of Genetic Medicine (IGM)
in 1999; provision of state of the art research space in the Miller Research Building in 2004;
introduction of The Genes to Society Medical School curriculum in 2009 that has genetics
and genetic-thinking as an organizing principle; and, most recently, provision of new space
and resources for the Johns Hopkins Genomics center that will bring together clinical and
research sequencing in one unit under the IGM and the Department of Pathology.
 The overall objective of the HG is to provide our students with a strong foundation in
basic science by exposure to a rigorous graduate education in genetics, genomics,
molecular biology, cell biology and biochemistry plus a core of medically-related courses
selected to provide knowledge of human biology in health and disease. Through seminars,
laboratory rotations and thesis work, our students are also exposed to a wide variety of
modern research technologies relevant to human genetics and learn the basic skills
necessary to become an independent investigator. The research activities of the 76 HG
preceptors are diverse and include human and model organism genetics and genomics,
developmental genetics, identification and analysis of genes and genetic variants
responsible for human monogenic disorders and complex traits, molecular cytogenetic,
quantitative genetics, gene therapy, oncogenetics, stem cell genetics, genome editing for the
production of cellular and animal models and for therapy of genetic disease and studies of
the ethical and societal consequences of the genetic revolution. This broad spectrum of
research activities in human genetics integrated with knowledge of human biology provides
virtually unlimited opportunities for our students to work on projects appealing to their
individual interests. The ultimate goal of our program is to produce independent, rigorous
thinking investigators who are well versed in human biology in health and disease and in all
aspects of human genetics and genomics. This education prepares our students to answer
important basic science questions and to translate this information into bio-medical
advances. The success of our graduates, who go on to productive academic careers in top
universities, private sector research, or careers using genetics in law and public policy
strongly supports this conclusion.

## Key facts

- **NIH application ID:** 10162608
- **Project number:** 5T32GM007814-40
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** DAVID VALLE
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $355,008
- **Award type:** 5
- **Project period:** 1980-07-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10162608

## Citation

> US National Institutes of Health, RePORTER application 10162608, Predoctoral Training Program in Human Genetics (5T32GM007814-40). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10162608. Licensed CC0.

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