# THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE

> **NIH NIH U24** · UNIVERSITY OF PENNSYLVANIA · 2020 · $1,151,283

## Abstract

Abstract/Summary
NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) is a one-stop access portal for
Alzheimer's disease genetics and serves as the data coordinating center for the Alzheimer's Disease
Sequencing Project (ADSP). ADSP has expanded substantially since NIAGADS submitted the renewal
application in 2016, including processing sequence data of up to 114,335 genomes from 119 cohorts (10
times what was anticipated initially) and three new major initiatives on machine learning analysis,
phenotype harmonization, and functional genomics. Neither NIA nor NIAGADS could have anticipated
the major growth or the new NIA initiatives when the original application was written, and it is
imperative that we augment the capacity of NIAGADS to maintain efficient operations with this
supplement request.
The proposed administrative supplement aims to augment the capacity of NIAGADS and maintain
efficient operations for ADSP support in order that NIA meets its NAPA Milestones. The request is
within the scope of the original research plan and includes four tasks: (1) additional programmer
support to maintain NIAGADS cloud data sharing service and its security; (2) develop tools for cloud-
based data analysis; (3) collaborate with Case Western Reserve University to enhance our cloud-based
computing infrastructure for ADSP data analysis; (4) expand NIAGADS outreach with a website for
disseminating AD genetics research to a wider audience.

## Key facts

- **NIH application ID:** 10162734
- **Project number:** 3U24AG041689-09S1
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** LI-SAN WANG
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,151,283
- **Award type:** 3
- **Project period:** 2012-04-01 → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10162734

## Citation

> US National Institutes of Health, RePORTER application 10162734, THE NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE (3U24AG041689-09S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10162734. Licensed CC0.

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