# Vanderbilt O'Brien Kidney Center - Core D - Clinical and Translational Core

> **NIH NIH P30** · VANDERBILT UNIVERSITY MEDICAL CENTER · 2021 · $205,400

## Abstract

ABSTRACT
The Clinical and Translational Core (Clinical Core) aims to facilitate patient-oriented research for
investigators spanning from clinical translational research to population epidemiology. Resources and
expertise will be pooled under the common Clinical Core umbrella to provide a wide range of clinical
translational research resources including, but not limited to access to biosamples, technical resources such as
sample analysis and biostatistical support and clinical data while increasing the efficiency of operations through
expert knowledge for the construction, implementation and interpretation of the studies. The primary
advantages of the Clinical Core are that 1) it enhances the quality of the experiments by providing a priori step-
wise design process; 2) it alleviates experimental constraints by providing access to a variety of clinical
research resources; and 3) it includes an infrastructure for data and sample coordination and storage. The
Clinical Core will accomplish these goals by establishing three Subcores: 1) Biorepository Subcore; 2) Human
Metabolic Phenotyping Subcore and 3) Clinical Epidemiology and Biostatistics Subcore. The internal and
external users will access these resources by: 1) direct requests for biosamples, including tissue; 2) request for
clinical and research data from large cohort studies, including BioVU and Research Derivative; 3) requesting
statistical support for design and interpretation of new, ongoing or completed studies; and 4) request for
analytical resources. For implementation and administration, the Clinical Core proposes to channel all
information and specimens into analytical, statistical, and bioinformatics services, thereby enhancing the utility
of these resources. The Clinical Core will also assist investigators in the process of communicating research
findings to stakeholders and members of target communities that are partners in the research process. In
accomplishing the goals, the Clinical Core will take advantage of available institutional resources, such as the
Vanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt Diabetes Research and
Training Center (DRTC) and Digestive Disease Research Center (DDRC).

## Key facts

- **NIH application ID:** 10163169
- **Project number:** 5P30DK114809-05
- **Recipient organization:** VANDERBILT UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** TALAT Alp IKIZLER
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $205,400
- **Award type:** 5
- **Project period:** 2017-09-08 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10163169

## Citation

> US National Institutes of Health, RePORTER application 10163169, Vanderbilt O'Brien Kidney Center - Core D - Clinical and Translational Core (5P30DK114809-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10163169. Licensed CC0.

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