# Cancer Center Support Grant

> **NIH NIH P30** · DARTMOUTH COLLEGE · 2020 · $328,000

## Abstract

Project Summary/Abstract: Norris Cotton Cancer Center (NCCC)
Norris Cotton Cancer Center (NCCC) at Dartmouth is dedicated to developing strategies to prevent and cure
cancer, through pioneering interdisciplinary research, and translating new knowledge into meaningful
preventive and therapeutic approaches. We seek to reduce the population's risk of cancer, control disease in
cancer patients, and enhance the well-being of cancer survivors. While pursuing resolution of these concerns
in general, as the only NCI-designated comprehensive cancer center in Northern New England, we are
particularly attentive to addressing the needs of the relatively rural, medically underserved residents of
Northern New England in the surrounding catchment area. Our approach includes engaging our 150 NCCC
faculty Members in collaborative efforts around six transdisciplinary unifying themes to address Cancer Control
(CC), Cancer Epidemiology (CE), Cancer Mechanisms (CM), Molecular Therapeutics (MT), Cancer Imaging &
Radiobiology (CIR), and Immunology & and Cancer Immunotherapy (ICI). Although organizationally based
within Dartmouth's Geisel School of Medicine, our academic faculty participation spans Dartmouth's College of
Arts & Sciences, Dartmouth's Thayer School of Engineering, as well as medical care providers in Dartmouth-
Hitchcock (DH) Medical Center, our clinical partner institution. We are engaged closely with campus-wide
initiatives in clinical and translational research (Dartmouth's CTSA) and population sciences (The Dartmouth
Institute). The Center advances work in NCCC-designated priority areas by providing developmental funds to
support the initial research efforts of new investigators, innovative and collaborative pilot projects, shared
resources, and access to new technologies and methodologies. Shared Resources are a key investment in
NCCC-wide core capabilities and nine are critical to facilitating cancer research: Biostatistics (BSR), Trace
Elements (TE), Genomics & Molecular Biology (GMB), Bioinformatics (BISR), Immune Monitoring & Flow
Cytometry (IMFC), Clinical Pharmacology (CP), Irradiation, Preclinical Imaging & Microscopy (IPIM);
Pathology (PSR), and Transgenic & Genetic Constructs (TGC). We also have organized an Office of Clinical
Research (OCR) to advance translation of research insights into clinical and population-based interventions.
The OCR presently manages 3,005 subjects enrolled on 437 active studies. Transdisciplinary research is
facilitated by NCCC's organization of 11 Clinical Oncology disease teams. This current application reviews
NCCC work that has resulted in 2,028 publications (nearly 17% in journals with impact factors >8) by the
Members. The NCCC externally funded cancer research portfolio, which currently exceeds $54M annually in
peer-reviewed support (>30% NCI), represents just under 50% of the entire peer-reviewed research portfolio at
Dartmouth, illustrating the ability of Cancer Center Senior Leadership to organize campus-...

## Key facts

- **NIH application ID:** 10164408
- **Project number:** 3P30CA023108-41S6
- **Recipient organization:** DARTMOUTH COLLEGE
- **Principal Investigator:** Steven D Leach
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $328,000
- **Award type:** 3
- **Project period:** 1997-08-04 → 2024-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10164408

## Citation

> US National Institutes of Health, RePORTER application 10164408, Cancer Center Support Grant (3P30CA023108-41S6). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10164408. Licensed CC0.

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