# Longitudinal Effects of Socioeconomic Disadvantage and Racial Discrimination on Health Among African Americans and Puerto Ricans

> **NIH NIH R01** · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2021 · $770,594

## Abstract

PROJECT SUMMARY/ABSTRACT
The proposed research would capitalize on a wealth of longitudinal data previously collected at key
developmental stages over a period of 27 years as part of the Harlem Longitudinal Development Study. It has
two major aims: The first is to identify the mediators of the relationships between social determinants of health
(i.e., socioeconomic disadvantage and ethnicity-based/racial discrimination) and allostatic load in a sample of
African Americans and Puerto Ricans entering midlife. The research proposal is guided by a contextual-
developmental model based in Phenomenological Variant of Ecological Systems Theory, as well as a
pathophysiological theory of stress (allostatic load). Second, the research will identify the differential
developmental trajectories of perceived ethnicity-based/racial discrimination from late adolescence to the early
forties, examine their associations with allostatic load and mental health in the early forties, and test the ability
of resilience resources to mitigate these associations. The sample for this study will consist of 400 male and
female African Americans and Puerto Ricans who were previously seen in adolescence (T1, T2), emerging
adulthood (T3), young adulthood (T4), and adulthood (T5, T6). Identifying the pathways through which risk and
protective factors for allostatic load operate will have important implications for public health by providing
targets for intervention and informing policy. Finding moderating constructs that can mitigate the deleterious
sequelae of chronic ethnicity-based/racial discrimination will highlight significant areas of resilience. Such a
focus on resilience not only moves away from a deficit perspective of people of color, but also has the potential
to transform policy and interventions by building on strengths, rather than treating deficits. A move in this
direction is an important step towards reaching the goal of eliminating the significant social and ethnic/racial
health disparities that plague the U.S. and realizing health equity for all.

## Key facts

- **NIH application ID:** 10164624
- **Project number:** 5R01MD012248-05
- **Recipient organization:** NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- **Principal Investigator:** Kerstin Pahl
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $770,594
- **Award type:** 5
- **Project period:** 2017-09-24 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10164624

## Citation

> US National Institutes of Health, RePORTER application 10164624, Longitudinal Effects of Socioeconomic Disadvantage and Racial Discrimination on Health Among African Americans and Puerto Ricans (5R01MD012248-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10164624. Licensed CC0.

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