# Analgesic Drug for Local Delivery by Fluoroscopy

> **NIH NIH R44** · INTERVENTIONAL ANALGESIX, INC. · 2020 · $1,586,882

## Abstract

Chronic pain affects 116 million Americans at a cost of $560 billion per year according to the Institute of
Medicine. 25.3 million adults had pain every day for the preceding 3 months. Current analgesic therapies
often fail in chronic pain and can lead to drug abuse. 18,893 Americans died from prescription opioids in
2014, 1.9 million were addicted to them. The enclosed application develops a non- opioid, non-addictive
analgesic drug for local delivery by fluoroscopy. Fluoroscopy is a type of medical imaging that shows an X-
ray image on a monitor in real time, much like an X-ray movie. During fluoroscopy an X-ray beam is passed
through the body. The image is transmitted to a monitor so the movement of an instrument through the body,
e.g., an injection needle, can be seen in detail. “Interventional pain” physicians are board certified specialists
trained in fluoroscopy. 4500 interventional pain physicians practice in the US performing >5 million
fluoroscopic procedures per year. Market research has identified interventional pain physicians and health
insurance managers as primary customers. The proposed commercial product has the potential to engender
a paradigm-shift in the treatment of hitherto intractable chronic locoregional pain. The studies proposed for
this Phase II award will advance commercial R&D to the clinical stage. Business confidential details are
presented under Specific Aims.

## Key facts

- **NIH application ID:** 10166737
- **Project number:** 1R44NS120840-01
- **Recipient organization:** INTERVENTIONAL ANALGESIX, INC.
- **Principal Investigator:** ANDREAS S. BEUTLER
- **Activity code:** R44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,586,882
- **Award type:** 1
- **Project period:** 2020-09-30 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10166737

## Citation

> US National Institutes of Health, RePORTER application 10166737, Analgesic Drug for Local Delivery by Fluoroscopy (1R44NS120840-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10166737. Licensed CC0.

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