# Mentoring and Neuroimaging Research on White Matter Pathology in Schizophrenia

> **NIH NIH K24** · BRIGHAM AND WOMEN'S HOSPITAL · 2021 · $188,938

## Abstract

Abstract
I am a clinical radiologist and neuroscientist by training. I have devoted my research
career to understand mechanisms, nature and time-course of white matter pathology in
schizophrenia. I am an Associate Professor in Departments of Radiology and Psychiatry
at Brigham and Women’s Hospital, Harvard Medical School. I also serve as Associate
Director of Psychiatry Neuroimaging Laboratory, Department of Psychiatry at BWH, and
as a co-Director of Center for Morphometric Analysis, Department of Psychiatry, and
Massachusetts General Hospital, where I have a secondary appointment as research
scientist. I have been conducting an NIH sponsored research since 2003, when I
received my first R03 award. I am currently PI on an NIMH R01 award, focusing on
Development of New Neuroimaging Biomarkers of Risk, Onset and Outcome of
Schizophrenia. I am also a PI on NIA funded R01 on understanding mechanisms of
brain development, maturation and aging through a set of neuroimaging tools and their
validation in rhesus monkeys. Those two grants together have the potential of delivering
validated neuroimaging biomarkers, which could be used to diagnose and monitor
neurobiological changes due to myelin loss and neuroinflammation in schizophrenia,
aging, and a whole list of other neuropsychiatric diseases where those changes are
involved. Besides my research, I am also involved in mentoring Harvard, MIT and BU
undergraduate and graduate thesis students, postdoctoral fellows (including T32 and
K23 awardees), foreign fellows, and summer students. I am also involved in
administrative work, as head of two large laboratories, at BWH and at MGH, and various
local and regional committees. Finally, I am getting involved in nonclinical and non-POR
research (through my ongoing and pending animal projects), and that takes away from
both my mentoring and my POR research. The K24 would protect time and help me to
focus on most important for my career development- mentoring (30%), further training
and new POR (20%), while devoting remaining 50% to ongoing neuroimaging research
in biomarkers of white matter changes in aging and schizophrenia.

## Key facts

- **NIH application ID:** 10166928
- **Project number:** 5K24MH110807-05
- **Recipient organization:** BRIGHAM AND WOMEN'S HOSPITAL
- **Principal Investigator:** Marek Kubicki
- **Activity code:** K24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $188,938
- **Award type:** 5
- **Project period:** 2017-05-09 → 2023-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10166928

## Citation

> US National Institutes of Health, RePORTER application 10166928, Mentoring and Neuroimaging Research on White Matter Pathology in Schizophrenia (5K24MH110807-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10166928. Licensed CC0.

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