# Data Archive for the Brain Initiative (DABI)

> **NIH NIH R24** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2021 · $1,228,899

## Abstract

ABSTRACT
The overarching goal of this project is to secure, link, and disseminate BRAIN Initiative data, including
electrophysiology, imaging, behavioral, and clinical data with all pertinent recording and imaging parameters,
coming from participating sites. Our plan for a Data Archive for the Brain Initiative (DABI) is in response to
RFA-MH-17-255.
The Laboratory of Neuro Imaging (LONI) at USC has established itself as a hub for delivering effective
informatics and analytics solutions in the context of big data for major projects in the study of a range of
neurological diseases. LONI has demonstrated and proven experience with variations in data descriptions,
data incompleteness, and data harmonization; we have built data portals and query engines for efficient search
and utilization, and we have, most importantly, enabled broad data (re-)use toward accelerated discovery. Just
as the ADNI (http://adni.loni.usc.edu/) project has been a powerful catalyst for success in biomarker research
in Alzheimer's disease, this project has the power to foster a similar and potentially greater level of success for
human neurophysiological data. Furthermore, we understand the needs of investigators who have collected
these data and their concerns associated with data sharing, in addition to the privacy of the subjects from
whom the data are collected.
We have the extensive infrastructure in place to handle such large-scale data as well as LONI's Pipeline
Processing Environment for streamlined integration of analytic tools. This platform will be designed with the
flexibility to integrate input from those awarded grants to address standardization of data (RFA-MH-17-256) as
well as those who design tools to interface with archives (RFA-MH-17-257).
We will receive and de-identify data of various modalities from the participating sites, incorporating analysis
tools previously developed at LONI and elsewhere, managing the data access systems, providing user
interfaces to explore, visualize, interpret, and download the data, and provide comprehensive information
about the projects and corresponding data through the public website that will be developed specifically for
DABI.
We aim to provide a tool for investigators that will decrease the burden of archiving the data once it has been
generated. We have already created a true community by having established good communication among our
group of collaborators from funded BRAIN Initiative programs. Furthermore, we will be working with industry
partners that are anticipated major sources of data to specifically streamline methods for data upload from
those sources.

## Key facts

- **NIH application ID:** 10166941
- **Project number:** 5R24MH114796-04
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Dominique Duncan
- **Activity code:** R24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,228,899
- **Award type:** 5
- **Project period:** 2018-09-05 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10166941

## Citation

> US National Institutes of Health, RePORTER application 10166941, Data Archive for the Brain Initiative (DABI) (5R24MH114796-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10166941. Licensed CC0.

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