# Centralized data management for the whole-brain atlas of cell types in the mouse

> **NIH NIH U19** · ALLEN INSTITUTE · 2021 · $1,194,784

## Abstract

Project Summary (Data Core):
As described for each of the molecular signatures, anatomy, functional measures and genetic tools research
segments, the Comprehensive Center on Mouse Brain Cell Atlas will be generating large scale datasets of
different modalities and originating from different institutions. The Data Core will provide centralized data
management systems to collect and integrate the diverse data collections and provide data processing and
mapping infrastructure and expertise to transform raw data into quantitative cell characterization features.
Within this Center, across the BRAIN Initiative Cell Census Network (BICCN) and across the community there
is an increasing need to enhance data interoperability and harmonization among data producers to allow
meaningful data integration and simplified data accessibility and reuse. Atlases and common coordinate
systems play a fundamental role in gathering, analyzing, communicating, and standardizing data. We will
develop data management systems to store and manage data and metadata generated from researchers
within the Center and facilitate the submission of data and analyses to the BCDC. We will develop tools and
methods to support the mapping of data to a mouse brain common coordinate system, and support
processing, quantification and analysis for cell type characterization, classification and census. Finally, the
Data Core will form a strong partnership with other BICCN centers and the BRAIN Cell Data Center (BCDC) to
collaboratively build up brain cell type atlases with broadly accessible common coordinate systems to integrate
and disseminate the brain cell census data.

## Key facts

- **NIH application ID:** 10168630
- **Project number:** 5U19MH114830-05
- **Recipient organization:** ALLEN INSTITUTE
- **Principal Investigator:** Lior S Pachter
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,194,784
- **Award type:** 5
- **Project period:** 2017-09-20 → 2023-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10168630

## Citation

> US National Institutes of Health, RePORTER application 10168630, Centralized data management for the whole-brain atlas of cell types in the mouse (5U19MH114830-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10168630. Licensed CC0.

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