# Center for Advanced Renal Microscopic Analysis

> **NIH NIH P30** · INDIANA UNIVERSITY INDIANAPOLIS · 2021 · $1,167,815

## Abstract

Abstract (Center Overview)
Indiana University has over the last twenty years developed a unique, highly interactive, integrated and
synergistic team of physicians, basic scientists, computer scientists, engineers and a highly trained and
committed technical support team, powered by cutting-edge equipment and technolog, to develop and utilize
intravital optical microscopy and 3D quantitative digital image analysis of the kidney. This scientific hub has
resulted in a highly productive Division of Nephrology with far-reaching interactions involving multiple
investigators on the IU medical school campus, Purdue University, Indiana University- Bloomington and
beyond. In particular, the existing O'Brien Center for Advanced Renal Microscopic Analysis has allowed our
biomedical base and outside users from around the world to benefit from the scientific expertise and equipment
available at the imaging center. The development and user-based customization of specialized techniques of
microscopy and quantitative analysis have been a hallmark of the existing P-30 center. Therefore, the primary
purpose of this proposal is to continue to offer and further develop an integrated approach to quantitative
intravital and tissue microscopy to facilitate molecular, cellular and genetic approaches to the study of disease
processes and their therapy to our biomedical base and investigators from around the world. We have added
a quantitative 3D tissue imaging core to address the need for specialized expertise and infrastructure to
support the collection and quantitative analysis of large-scale, high-content and high resolution microscopy
data. In doing so, this Center will provide renal/urological researchers with a novel set of research methods,
quantitative analysis tools and fluorescent biosensors or probes not available elsewhere, tools that will facilitate
biomedical research, drug discovery, and therapeutic approaches to Kidney and Urologic diseases.

## Key facts

- **NIH application ID:** 10169412
- **Project number:** 5P30DK079312-15
- **Recipient organization:** INDIANA UNIVERSITY INDIANAPOLIS
- **Principal Investigator:** Pierre C Dagher
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,167,815
- **Award type:** 5
- **Project period:** 2007-08-03 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10169412

## Citation

> US National Institutes of Health, RePORTER application 10169412, Center for Advanced Renal Microscopic Analysis (5P30DK079312-15). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10169412. Licensed CC0.

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