# Gene Ontology Consortium Supplemental

> **NIH NIH U41** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2020 · $90,217

## Abstract

Project Summary
The overall goal of the proposal is to perform extensive preliminary work that would ultimately
lead to interoperability and to automatic data exchange between the GO and Reactome
resources. We do not expect to fully achieve interoperability with a supplement, but, rather, the
supplement will support the work needed to identify all the issues that need to be addressed,
and to test solutions for these issues. The work proposed in this supplement will enable us to
develop a detailed plan which would be necessary for future grant applications. In addition,
based on an initial analysis that GO and Reactome have already performed together, we also
expect substantial short-term benefits from the supplement: it will allow us to achieve
interoperability for nearly all metabolic pathways (though not signaling pathways). For the
broader genomics community, this work will result in a more fully interoperable set of major
genomics resources and a model for coordination among resources to identify and share
definitive sources of reference information for improved curation efficiency with minimal
redundancy. Our work will utilize BioPAX-formatted data, thereby also enhancing interoperability
of GO with any resource that utilizes BioPAX (these resources are integrated in
PathwayCommons). This interoperability will also eventually make curation more efficient, as
information curated in one project will greatly accelerate curation in other projects.

## Key facts

- **NIH application ID:** 10170036
- **Project number:** 3U41HG002273-20S1
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Judith A Blake
- **Activity code:** U41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $90,217
- **Award type:** 3
- **Project period:** 2001-01-19 → 2022-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10170036

## Citation

> US National Institutes of Health, RePORTER application 10170036, Gene Ontology Consortium Supplemental (3U41HG002273-20S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10170036. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*