# Administrative Supplement (P30AG035982): Supplement for Additional Neuroimaging for the KU ADC.

> **NIH NIH P30** · UNIVERSITY OF KANSAS MEDICAL CENTER · 2020 · $380,970

## Abstract

PROJECT SUMMARY/ ABSTRACT
 This administrative supplement will provide additional neuroimaging for the University of Kansas
Alzheimer's Disease Research Center (KU ADRC, P30 AG035982). These funds will be used to support the
acquisition of FDG-PET and MRI scans of KU ADRC Clinical Core participants who are cognitively intact that
will help both contribute to the sharable SCAN repository at the National Alzheimer's Coordinating Center
(NACC) and build our imaging database for translational studies involving genetics and omics data.
 These funds will allow us to collect 120 SCAN harmonized MRI and FDG-PET neuroimages in our
understudied cohort of cognitively intact individuals who also have genetic, cognitive, plasma, and serum data.
We propose to collect neuroimaging data on 120 of these understudied, cognitively normal cohort participants
(CN) to build on the neurodegeneration portion of the ATN classification framework (MRI and FDG-PET
neuroimages). We propose to combine this ATN classification with deep phenotyping of these participants
through imaging genetics analysis in collaboration with our mitochondrial and nuclear genetic data (MGM Core)
to characterize how mitochondrial and metabolic dysfunction contribute to AD risk. These funds give us an
opportunity to grow an imaging dataset that is tailored to the metabolic and mitochondrial focus of our KU
ADRC. Achieving the aims of this Administrative Supplement will allow our KU ADRC to contribute
neuroimaging data for SCAN to QC and harmonize data for the other ADRC sites.
 These scans are feasible within the one-year timeframe of an Administrative Supplement based on our
yearly scheduled visits for these participants. These sequences will add to our portfolio of sequences that will
be shared with other sites within and beyond the NIA ADRC network.

## Key facts

- **NIH application ID:** 10170917
- **Project number:** 3P30AG035982-10S1
- **Recipient organization:** UNIVERSITY OF KANSAS MEDICAL CENTER
- **Principal Investigator:** RUSSELL H. SWERDLOW
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $380,970
- **Award type:** 3
- **Project period:** 2011-08-15 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10170917

## Citation

> US National Institutes of Health, RePORTER application 10170917, Administrative Supplement (P30AG035982): Supplement for Additional Neuroimaging for the KU ADC. (3P30AG035982-10S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10170917. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*