# Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (NIA/AA IMPACT-AD) Course

> **NIH NIH U13** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2021 · $74,999

## Abstract

Project Summary
It has been nearly 15 years since the last FDA approval for a new treatment for Alzheimer's Disease and Related
Dementias (ADRD). Critical to the mission to improve the available therapies and curb the public health impact
of ADRD will be a new generation of ADRD scientists, especially scientists with the unique training and skills
necessary to design and perform clinical trials. This training is rarely provided through the traditional course of
medical or biostatistical education. As a result, there is a dearth of well-trained ADRD clinical trialists. Moreover,
there is very limited diversity among the current group of active ADRD trial investigators. To develop improved
therapies for ADRD, multidisciplinary expertise in clinical trials will be necessary, including medical specialists
but also expertise in biostatistics, trial design, biomarkers, ethics, and informatics. This proposal requests support
to establish a first-of-its-kind training program in the essential elements of ADRD trials. The Institute on Methods
and Protocols for the Advancement of Clinical Trials in ADRD (IMPACT-AD) Course will leverage the full
infrastructure and expertise of the Alzheimer's Clinical Trials Consortium (ACTC) affiliated faculty. IMPACT-AD
will be conducted annually to attract and train the next generation of ADRD clinical trialists, with a particular focus
on improving the diversity of ADRD clinical investigators across race/ethnicity, gender, and scientific/professional
backgrounds. IMPACT-AD seeks to provide a diverse range of clinicians, scientists and researchers with a
modern and robust training in the design and conduct of ADRD clinical trials.

## Key facts

- **NIH application ID:** 10172825
- **Project number:** 5U13AG067696-02
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Joshua Grill
- **Activity code:** U13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $74,999
- **Award type:** 5
- **Project period:** 2020-06-01 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10172825

## Citation

> US National Institutes of Health, RePORTER application 10172825, Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (NIA/AA IMPACT-AD) Course (5U13AG067696-02). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10172825. Licensed CC0.

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