# Capacity Development - Nanopore MinION

> **NIH FDA U19** · WASHINGTON STATE DEPARTMENT OF HEALTH · 2020 · $127,358

## Abstract

While the Illumina platform is the most widely used technology in whole genome sequencing 
(WGS), an emerging technology shows exciting promise. Because the Oxford Nanopore 
technology produces very long reads, it is possible to ‘close’ genomes, identifying chromosomes 
from plasmids. Combining bioinformatics tools to close the genome with tools to identify alleles 
contributing to AR conditions, it will be possible to develop a bioinformatics pipeline to determine 
the location of the alleles within a genome. WA PHL plans to develop these tools along with a 
laboratory protocol for routine use of the MinION in AR analyses, and validate these paths for 
clinical reporting. WAPHL holds several key elements making this project feasible, including two 
microbiologists already trained in the technology, a resident bioinformaticist, an AWS account 
as an environment to develop analysis tools, and several microbiologists already trained in the 
concepts of WGS.

## Key facts

- **NIH application ID:** 10173519
- **Project number:** 1U19FD007085-01
- **Recipient organization:** WASHINGTON STATE DEPARTMENT OF HEALTH
- **Principal Investigator:** Philip Dykema
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2020
- **Award amount:** $127,358
- **Award type:** 1
- **Project period:** 2020-09-01 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10173519

## Citation

> US National Institutes of Health, RePORTER application 10173519, Capacity Development - Nanopore MinION (1U19FD007085-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10173519. Licensed CC0.

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