# CAHFS Method Development and Validation; Discipline D Track 3; 7/1/2020-6/30/2021

> **NIH FDA U19** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2020 · $28,228

## Abstract

Discipline D Track 3: Method Development and Method Validation 
Project Summary 
The FDA’s utilization of chemical analysis is critical to the agency’s ability to protect the U.S. food supply 
from unsafe chemical contamination. There are continuing needs for new analytical methods and 
techniques to handle the challenges involved with new food matrices and to make effective use of new 
and more efficient analytical technology. The purpose of this project is to provide funding for 
preliminary investigations into new analytical approaches, method extensions to new food matrices, and 
multi-laboratory research studies. 
The Toxicology Section of the California Animal Health and Food Safety Laboratory (CAHFS) has 
extensive experience in method development and extension projects and evaluation of new 
technologies. The nature of veterinary analytical toxicology is such that there are constant requirements 
for new methods to be developed. Some of these methods are required to handle single events of 
toxicosis in animals while others are designed to become routine methods for long-term use. The ability 
to execute such development projects is integral to the Section’s mission of assuring the health of 
agricultural animals and the safety of their feeds in California. 
The Section maintains a variety of different types of instrumentation allowing for flexibility in analyte 
detection and the ability to analyze a wide variety of matrix types. CAHFS personnel are highly 
experienced in handling many types of method development projects. The section has worked 
collaboratively with the FDA to develop and validate a number of methods in the past and has had 
notable success in rapid method development in response to emergencies in the food supply. As part of 
this project, CAHFS has proposed a specific method development project for each of the five years 
covered by the grant. The methods proposed are intended to increase our ability to detect human food 
and animal feed contamination and prevent those commodities from injuring humans or animals. 
In summary, funding from this grant will allow CAHFS to continue to serve as a valued partner to the 
FDA in the exploration and development of new analytical chemistry methods and technologies.

## Key facts

- **NIH application ID:** 10173540
- **Project number:** 1U19FD007066-01
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** ROBERT HOWARD POPPENGA
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2020
- **Award amount:** $28,228
- **Award type:** 1
- **Project period:** 2020-09-01 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10173540

## Citation

> US National Institutes of Health, RePORTER application 10173540, CAHFS Method Development and Validation; Discipline D Track 3; 7/1/2020-6/30/2021 (1U19FD007066-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10173540. Licensed CC0.

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