# Mentoring Research Excellence in Aging and Regenerative Medicine

> **NIH NIH P20** · TULANE UNIVERSITY OF LOUISIANA · 2021 · $2,266,161

## Abstract

SUMMARY
 Aging is a biological process that is the major risk factor for chronic disease and degeneration during the
lifespan. However, it is beginning to be appreciated that disease and degeneration impinge on the aging
process, in something perhaps akin to a feedback loop. This suggests that a better knowledge of one
contributes to an understanding of the other. Furthermore, development of therapeutic interventions still must
address the degenerative disorders of aging, while the search for broad interventions that target the biological
aging process itself continues. The demographic and social developments associated with an aging
population point to a real and deepening need for researchers who will provide the basic knowledge on aging
that can be translated into solutions that are broadly applicable. Importantly, these researchers must more and
more frequently be able to communicate effectively with practitioners in other disciplines and even to become
part of multidisciplinary teams. The proposed Phase II COBRE in Aging and Regenerative Medicine will help
fill this national need by mentoring junior investigators in the aging field within an interactive and
multidisciplinary environment, while creating a dynamic center in which biomedical science targeting aging is
practiced. The focus here is biomedical research with translation firmly in mind. However, this COBRE
program is embedded within the multidisciplinary Tulane Center for Aging, and thus it can serve the purposes
of addressing the broader challenges of an aging society. Notwithstanding these overarching goals, the
individual research projects that are offered in this application have the promise of generating important new
insights into a few focused areas of biological aging and regeneration. These projects build on our successes
in COBRE Phase I, targeting central nervous system aging, immune system aging, degenerative disorders of
the brain and musculoskeletal system, as well as the larger issues surrounding cell senescence and chronic
inflammation.

## Key facts

- **NIH application ID:** 10173804
- **Project number:** 5P20GM103629-10
- **Recipient organization:** TULANE UNIVERSITY OF LOUISIANA
- **Principal Investigator:** S MICHAL JAZWINSKI
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $2,266,161
- **Award type:** 5
- **Project period:** 2012-08-01 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10173804

## Citation

> US National Institutes of Health, RePORTER application 10173804, Mentoring Research Excellence in Aging and Regenerative Medicine (5P20GM103629-10). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10173804. Licensed CC0.

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