# Immunologic Basis of Resistance and Hypersensitivity

> **NIH NIH T32** · BRIGHAM AND WOMEN'S HOSPITAL · 2021 · $495,511

## Abstract

Project Summary
This continuation of an established training program seeks to prepare qualified M.D., Ph.D., and M.D./Ph.D.
candidates for academic careers in the field of allergy and immunology. Support is again requested for seven
postdoctoral trainees having either a M.D. or Ph.D. degree or both. The training program emphasizes three
major areas: basic science, translational science, and clinical science. The trainees focused in basic science
learn techniques and concepts of immunopharmacology, immunochemistry, and cellular and molecular
immunology. Areas of emphasis include the basic biology of mast cells, lipid mediators, dendritic cells, innate
lymphoid cells, and animal models of allergic disease. Trainees in translational science paths incorporate
informatic approaches to analyze genetic, genomic, and unbiased sequencing or metabolomic data to
understand the mechanistic basis of human allergic diseases. Such trainees may also employ bench side
approaches to studies using human cells and tissues. Trainees in clinical sciences may focus on epidemiology
or clinical trials. The faculty are highly accomplished investigators with extensive mentoring track records and
substantial extramural grant support. The three-year research training period is designed so that each trainee
learns a range of techniques and approaches, gains a broad understanding of the innate and adaptive immune
host responses, and establishes a template for an early career research focus. This time frame also permits
the trainee, along with his or her mentor and Mentoring Subcommittee, to plan for post-fellowship career
development, with the goal of defining a path in academia that is commensurate with the trainee’s developing
skills and interests. The research experience is enhanced by didactic course work, as well as workshops in
grant writing, manuscript composition, and lab management. The program continues to be highly successful,
with over 75% of the graduates in the past decade having full-time academic appointments, many of whom are
primarily research based with independent NIH support.

## Key facts

- **NIH application ID:** 10174696
- **Project number:** 5T32AI007306-36
- **Recipient organization:** BRIGHAM AND WOMEN'S HOSPITAL
- **Principal Investigator:** Joshua A Boyce
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $495,511
- **Award type:** 5
- **Project period:** 1985-07-01 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10174696

## Citation

> US National Institutes of Health, RePORTER application 10174696, Immunologic Basis of Resistance and Hypersensitivity (5T32AI007306-36). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10174696. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*