# A High-Performance 3T MRI Scanner for Brain Imaging

> **NIH NIH S10** · DUKE UNIVERSITY · 2021 · $1,800,000

## Abstract

Project Summary/Abstract
The national emphasis on improving the understanding of our brains (e.g. the BRAIN initiative, the Human
Connectome Project) has pushed brain imaging to the forefront of scientific research. The inherent
advantages of high resolution and noninvasiveness have made magnetic resonance imaging (MRI) one of the
predominent methods for brain research in humans. We are among the leaders in developing innovative MRI
methodologies and applying them to investigate the working mechanisms of the human brain. Through a
two-year collaboration with GE Healthcare, and funded by our institutional funds, we successfully co-
developed and installed a state-of-the-art prototype 3T MRI that has a high-power torque-balanced gradient
coil, high-channel-count RF arrays with GE's AIR TechnologyTM, a fast array processor for dynamic image
processing and correction, and a suite of advanced pulse sequences, all of which are designed to achieve the
highest possible spatial resolution, spatial fidelity, imaging speed, temporal stability, and sensitivity. This
prototype 3T scanner will continue to undergo technological upgrades to stay at the forefront of MRI
technology, and support our advanced technical research activities as well as a portion of our neuroscience
applications that can tolerate periodic hadrware upgrades. However, this prototype 3T scanner has reached
full capacity over the past year, as a result many of our neuroscience studies do not have ready access to these
critical MRI technologies. To accommodate the remaining scan hours required by our 38 NIH projects, we are
requesting funds to fully upgrade our existing MR750 3T MRI, with the exception of the main magnet to save
cost, to the product GE UltraHigh Performace (UHP) 3T system running on the latest Premier platform. This
new state-of-the-art 3T scanner is largely based on our prototype 3T MRI scanner, but has more constant
hardware and software features (standard for a product scanner) for neuroscience applications that require
both longitudinal and cross-sectional comparisons among human subjects. This HEI S10 project, titled “A
High-Performance 3T MRI Scanner for Brain Imaging”, is submitted by 25 NIH-supported investigators who
primarily conduct neuroimaging research at the Brain Imaging and Analysis Center (BIAC) at Duke
University Medical School. Our collaborating scientists have found that the high spatial and teporal
resolutions, high imaging speed, and high signal-to-noise ratio of this new 3T UHP MRI are must-haves in
modern brain imaging research. With our outstanding technical and management infrastructure, BIAC has
been serving NIH-funded investigators for nearly two decadeds. We are thus confident that we will effectively
and efficiently manage this shared high-end instrument to give our users the best imaging tools to investigate
human brains in health and in disease, meeting the ever increasing demand from our neuroscience
investigators and their NIH-sponsored rese...

## Key facts

- **NIH application ID:** 10175380
- **Project number:** 1S10OD028544-01A1
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** ALLEN W SONG
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,800,000
- **Award type:** 1
- **Project period:** 2021-06-01 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10175380

## Citation

> US National Institutes of Health, RePORTER application 10175380, A High-Performance 3T MRI Scanner for Brain Imaging (1S10OD028544-01A1). Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/grant/nih/10175380. Licensed CC0.

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