# Preferences for PrEP in Tanzanian Women at Heightened Risk of HIV Infection

> **NIH NIH K01** · JOHNS HOPKINS UNIVERSITY · 2020 · $53,486

## Abstract

Project Summary
The purpose of this Mentored Research Scientist Career Development Award (K01) application is to develop
Dr. S. Wilson Beckham’s career as an independent investigator in implementation science to optimize
evidence-based HIV interventions in low-income countries, particularly among sexual and gender minorities.
This K01 will provide the necessary support to achieve the following goals: 1) to become an expert in
implementation science theories and methods in public health; 2) to gain training in the theory and application
of stated-preferences methods, particularly discrete-choice experiments (DCE); 3) to conduct preference
heterogeneity analyses of stated-preference data using latent class finite-mixtures models; 4) to become an
expert in pre-exposure prophylaxis (PrEP) implementation research. To support these goals, Dr. Beckham has
a mentoring team of his primary mentor, Dr. Deanna Kerrigan, a specialist in implementation of community-
based HIV interventions for high-risk women; three co-mentors, Dr. John FP Bridges, an expert in stated-
preferences methods; Dr. Chris Beyrer, a leading HIV researcher with expertise in PrEP implementation for
high-risk populations; and Dr. Noya Galai, a biostatistician who applies her skills to the development and
application of methods to public health, and a collaborater, Dr. Jessie Mbwambo, a leading researcher in sub-
Saharan Africa (SSA), specializing in implementing HIV interventions for high-risk populations collaborators at
Emory University, Drs. Patrick Sullivan and Travis Sanchez. Given the high burden of HIV among men who
have sex with men (MSM), integrating PrEP into HIV services is an urgent priority and requires implementation
science research to identify optimal patient-focused strategies and drug formulations (e.g. tablet, injectable,
cervical ring) that are acceptable to the intended populations and reaffirm their dignity, rights, and choice. The
goal of this study is to measure MSM’s preferences for injectable PrEP and explore healthcare provider-level
challenges, to inform future optimal implementation of PrEP into community-based interventions. To achieve
these goals, this study has the following research aims: 1) Quantify MSM’s stated preferences for PrEP by
designing and conducting a discrete choice experiment (DCE) using key attributes of long-acting injectable
PrEP among n=2,241 MSM in the US. This aim will embed and analyze a DCE in the American Men’s Internet
Survey (AMIS). 2) Identify preference heterogeneity across the different attributes of PrEP using a latent class
finite-mixture model to account for differences between groups of respondents (“latent classes”). 3) Identify
barriers and facilitators to healthcare providers’ willingness to prescribe LAI-PrEP to MSM and develop a
provider readiness tool, based on the adaptable Tailored Implementation for Chronic Diseases. This aim will
employ semi-structured interviews among providers of HIV-related healthcare (n=28), ...

## Key facts

- **NIH application ID:** 10175739
- **Project number:** 3K01MH114715-04S1
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Sam Wilson Cole
- **Activity code:** K01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $53,486
- **Award type:** 3
- **Project period:** 2017-09-01 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10175739

## Citation

> US National Institutes of Health, RePORTER application 10175739, Preferences for PrEP in Tanzanian Women at Heightened Risk of HIV Infection (3K01MH114715-04S1). Retrieved via AI Analytics 2026-07-18 from https://api.ai-analytics.org/grant/nih/10175739. Licensed CC0.

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