# Zeiss Lightsheet 7 microscope

> **NIH NIH S10** · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2021 · $559,336

## Abstract

Project Summary
This request is for funds to purchase a Zeiss Light Sheet 7 microscope. This instrument will be
housed, managed, and maintained by the Optical Imaging Core Facility (OIF) at UT Health San
Antonio (UT Health SA), which is jointly managed by UT Health SA and the Mays Cancer
Center. The OIF supports 70 NIH-funded laboratories. Last year alone, the OIF supported 92
externally funded research projects with a total award amount of more than $55 million. As a
component of Mays Cancer Center, an NCI designated cancer center, the OIF received an
“Outstanding” rating during the recent on site visit for the NIH/NCI P30 grant renewal. The type
of instrument requested is currently unavailable at UT Health SA and at any other institutions in
the city of San Antonio. The acquisition of this new imaging modality is considered essential in
order for the OIF to continue providing the needed services to our research community, in
particular, for achieving rapid, low toxicity, high-resolution, three-dimensional imaging of a broad
range of specimens for a large number of NIH-funded research projects. The new instrument is
particularly critical to the major users listed in the proposal, whose highly competitive and
innovative research is dependent on the availability of this instrument. Investigators, including
both well-established and new, from diverse research areas, will greatly benefit. The new
instrument can truly lead to a better understanding basic biological systems and to develop
novel therapeutic strategies in treating many diseases states, including cancer, brain injury,
degenerative neurological disease, dental pain, vision disease, osteoporosis and bone loss, and
digestive disease. The availability of this new instrument will also stimulate other investigators at
UT Health SA and nearby institutions to move their research into exciting and highly competitive
new directions. Overall, this acquisition will without a doubt, significantly impact a large number
of NIH-funded investigations covering an expansive array of disciplines in biomedical research.

## Key facts

- **NIH application ID:** 10176906
- **Project number:** 1S10OD030383-01
- **Recipient organization:** UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- **Principal Investigator:** Exing Wang
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $559,336
- **Award type:** 1
- **Project period:** 2021-06-15 → 2022-06-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10176906

## Citation

> US National Institutes of Health, RePORTER application 10176906, Zeiss Lightsheet 7 microscope (1S10OD030383-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10176906. Licensed CC0.

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