# Upgrading the CVID Biosensor Core Facility with a Biacore 8K instrument

> **NIH NIH S10** · UNIVERSITY OF MARYLAND BALTIMORE · 2021 · $438,939

## Abstract

Project Summary/Abstract
As tremendous advances have occurred in genomic biology, gene sequencing technologies, and
proteomic technologies, attention is increasingly focusing on gene products, most of which
function by interacting with other gene products. A comprehensive understanding of physiological
systems requires an in-depth definition of quantitative interactions between molecules. Biosensor
technologies provides a powerful approach to define these interactions in label-free systems.
Here we seek funds to upgrade the Biosensor Core facility in the Center of Vascular and
Inflammatory Diseases (CVID) at the University of Maryland School of Medicine by the purchase
of a Biacore 8K instrument. The major users of this Core have extensive expertise employing
surface plasmon resonance technology with over 45 peer-reviewed publications employing the
technology. The new instrument (Biacore 8K) will be integrated into the CVID Biosensor Core
Facility and with the Center for Innovative Biomedical Resources (CIBR), the Administrative home
for the University of Maryland School of Medicine Core facilities, thus providing the resource for
our growing research community. The Biacore 8K will enhance the research of the Major users
and Minor users by increasing the throughput capacity, by enhancing a more reproducible and
optimized experimental design, and by increasing the sensitivity for measuring the interaction of
low molecular weight molecules.

## Key facts

- **NIH application ID:** 10176937
- **Project number:** 1S10OD030379-01
- **Recipient organization:** UNIVERSITY OF MARYLAND BALTIMORE
- **Principal Investigator:** Dudley K. Strickland
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $438,939
- **Award type:** 1
- **Project period:** 2021-07-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10176937

## Citation

> US National Institutes of Health, RePORTER application 10176937, Upgrading the CVID Biosensor Core Facility with a Biacore 8K instrument (1S10OD030379-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10176937. Licensed CC0.

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