# NMR Console and Prodigy CryoProbe

> **NIH NIH S10** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2021 · $600,000

## Abstract

Project Summary
A group of NIH supported investigators requests funds to purchase a NMR cryoprobe and upgrade the console
of a 600 MHz NMR spectrometer. This equipment will significantly increase the signal sensitivity of an existing
shared spectrometer that is housed in the NMR Laboratory of the UCLA Molecular Instrumentation Center Core
Facility and bring high sensitivity NMR detection of heteronuclei to the facility. Specifically, we request funds to
purchase a broadband Bruker Prodigy CryoProbe that increases NMR signal sensitivity by a factor of 2-4 over
the conventional NMR probe. Additionally, we request funds to replace the outdated Bruker Avance I NMR
console that was installed in 2002, with an Avance Neo 600 High Performance Digital console, which is needed
to support the new cryoprobe. The new instrumentation is not only expected to be considerably more sensitive,
but also more reliable than the existing NMR console and probe, and it will help to relieve the oversaturation
usage of other magnets in the facility. The new equipment will be managed by two experienced Ph.D.-level staff
scientists. Also, if this grant is awarded, UCLA has committed funds to purchase a 60X sample changer to further
optimize the resources in the facility, increase usage capacity, reduce the risk for accidental failure, and show
our institutional commitment to excellence in research supported by state-of-the-art instrumentation.

## Key facts

- **NIH application ID:** 10177110
- **Project number:** 1S10OD028644-01A1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** Neil K. Garg
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $600,000
- **Award type:** 1
- **Project period:** 2021-09-01 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10177110

## Citation

> US National Institutes of Health, RePORTER application 10177110, NMR Console and Prodigy CryoProbe (1S10OD028644-01A1). Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/grant/nih/10177110. Licensed CC0.

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