# Self-regulation of Health Promotion: the Roles of Momentary Variability in Working Memory Capacity and Neurocognitive Aging

> **NIH NIH R00** · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · 2021 · $243,976

## Abstract

Project Summary
The ability to instantiate and maintain goal representations in short-term (“working”) memory (WM) is central to
human capacities for flexible thought and goal-directed behavior. Critically, human aging is associated with a
decline in the ability to control what gains access to and is maintained in WM (“executive” hypothesis of aging).
While the executive hypothesis has been well-studied in recent years in context of neurocognitive aging, it
remains poorly understood whether these changes are consequential to goal-directed behavior in daily life. As
a novel approach to this issue, in the present set of studies we will examine the contribution of brain imaging,
lab-based, and momentary (i.e. daily/within-day) assessments of WM to self-regulation of health promotion
behavior (specifically, physical activity). Recent evidence shows that individual differences in executive control
are a primary determinant of an individual’s ability to successfully translate physical activity goals into
daily behavior (i.e. self-regulatory capacity). However, this has been understudied in middle-aged and
older adults in whom the efficiency of WM and affiliated brain networks are subject to alteration. An important
next step is to examine WM and self-regulation at the level of behavior in naturalistic settings. The NIH/NIA
K99/R00 Pathway to Independence Award is being sought to provide the PI training in ambulatory
measurement methodology (ecological momentary assessments, EMA) and the resources to conduct a novel
longitudinal study of younger, middle-aged, and older adults focused on the role of momentary WM abilities in
self-regulation of physical activity. The use of smart phone-based EMA will provide a glimpse into the daily
lives of study participants, providing a novel opportunity to examine how neurocognitive resources and lab-
based assessments of control over WM project out to intra-individual trajectories of cognition and behavior.
The current proposal will:
1) Examine the contribution of WM to self-regulation of health promotion behavior and health/well-
 being outcomes in middle-aged and older adults. Individuals who self-report high self-regulation
 achieve generally superior health and well-being outcomes. However, the role control over WM
 processing plays in moderating these achievements has been understudied.
2) Develop novel ambulatory measures of WM capacity. Lab-based executive control tasks are less
 suitable for ambulatory deployment. EMA of WM capacity will place objective assessment of controlled
 cognition in close proximity of real-time self-regulation of behavior.
3) Examine how individual differences in the neurocognitive resources that underlie WM
 processing project out into intra-individual trajectories of health promotion behavior. We expect
 that age-related declines/maintenance of the neurocognitive resources that support WM processing will
 play a key role in determining an individual’s capacity to self-regulate phys...

## Key facts

- **NIH application ID:** 10177829
- **Project number:** 5R00AG056670-05
- **Recipient organization:** PENNSYLVANIA STATE UNIV HERSHEY MED CTR
- **Principal Investigator:** Jonathan G. Hakun
- **Activity code:** R00 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $243,976
- **Award type:** 5
- **Project period:** 2019-09-01 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10177829

## Citation

> US National Institutes of Health, RePORTER application 10177829, Self-regulation of Health Promotion: the Roles of Momentary Variability in Working Memory Capacity and Neurocognitive Aging (5R00AG056670-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10177829. Licensed CC0.

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