# Pilot Research Project Core NIDA "COE" Transcriptomics, Systems Genetics and the Addictome

> **NIH NIH P30** · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · 2021 · $27,758

## Abstract

Addiction is a highly complex disease with risk factors that include genetic variants and differences in
development, sex, and environment. The long term potential of precision medicine to improve drug treatment
and prevention depends on gaining a much better understanding how genetics, drugs, brain cells, and
neuronal circuitry interact to influence behavior. There are serious technical barriers that prevent researchers
and clinicians from incorporating more powerful computational and predictive methods in addiction research.
The purpose of the NIDA P30 Core Center of Excellence in Omics, Systems Genetics, and the Addictome
is to empower and train researchers supported by NIH, NIDA, NIAAA, and other federal and state institutions
to use more quantitative and testable ways to analyze genetic, epigenetic, and the environmental factors that
influence drug abuse risk and treatment. Our Pilot core is catalyzing new collaborations among early career
investigators in the field of addiction research. In sum the Center is a national resource for reproducible
research in addiction. We are centralizing, archiving, distributing, analyzing and integrating high quality data,
metadata, using open software systems in collaboration with many other teams of researchers. Our goal is to
help build toward an NIDA Addictome Portal that will include all genomic research relevant to addiction
research.

## Key facts

- **NIH application ID:** 10177982
- **Project number:** 5P30DA044223-05
- **Recipient organization:** UNIVERSITY OF TENNESSEE HEALTH SCI CTR
- **Principal Investigator:** ROBERT W. WILLIAMS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $27,758
- **Award type:** 5
- **Project period:** 2017-08-01 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10177982

## Citation

> US National Institutes of Health, RePORTER application 10177982, Pilot Research Project Core NIDA "COE" Transcriptomics, Systems Genetics and the Addictome (5P30DA044223-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10177982. Licensed CC0.

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