# Translational Post-doctoral Training in Neurodevelopment

> **NIH NIH T32** · BOSTON CHILDREN'S HOSPITAL · 2021 · $104,248

## Abstract

Project Summary/Abstract:
The Translational Post-doctoral Training in Neurodevelopment (TPND) Program at Boston Children's Hospital
is designed to provide promising post-doctoral neuroscience investigators (MD, PhD or MD/PhD) with
advanced training in essential translational topics ranging from preclinical considerations through
implementation of clinical trials for individuals with a range neurodevelopmental disorders. Large numbers of
children, adolescents, and adults are affected by neurodevelopmental disorders that begin early in life, are
rooted in aberrant brain circuitry, and have profound short- and long-term consequences on critical domains of
development, cognition, social interaction, and behavioral regulation; yet most available medical and
psychological treatments have had limited impact on the course of neurodevelopmental disorders. We
propose to build on the significant strengths of the Translational Neuroscience Center (TNC) and the
Laboratories of Cognitive Neuroscience at Boston Children's Hospital and Harvard Medical School to provide
trainees with research experiences ranging from pre-clinical and cognitive neuroscience labs through clinical
trial involvement in neurodevelopmental disorders. In addition, a key premise of this program is that effective
research training in the field of translational neuroscience requires both mentors with expertise in areas across
the continuum of translational research with neurodevelopmental disorders and ongoing programs to support
the trainees to conduct innovative, high impact translational research. The 17 faculty mentors will involve
trainees over a 2 year period (2 new entrants per year) with a range of state of the art methods in translational
neurodevelopmental science that reflect core areas of the TNC program including basic science and
translational methods as well as application to clinical populations in therapeutic trials for neurodevelopmental
disorders. This research experience will be supplemented with both didactic and clinical immersion
experiences designed to provide trainees with the skills needed to be successful independent investigators in
this critical and emerging field. Ultimately this research experience will yield treatments that have an impact on
the field by reducing the burdens and costs of care and costs to society that is now associated with
neurodevelopmental disorders. In addition, the TPND will develop models of interdisciplinary research training
for promising young scientists that will have a transformative impact on the field.

## Key facts

- **NIH application ID:** 10178112
- **Project number:** 5T32MH112510-05
- **Recipient organization:** BOSTON CHILDREN'S HOSPITAL
- **Principal Investigator:** CHARLES Alexander NELSON
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $104,248
- **Award type:** 5
- **Project period:** 2017-07-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10178112

## Citation

> US National Institutes of Health, RePORTER application 10178112, Translational Post-doctoral Training in Neurodevelopment (5T32MH112510-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10178112. Licensed CC0.

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