# Genomic Resource Grant for the PhenX Toolkit - expansion and sustainabilityPhenX Supplement for COVID-19 Research

> **NIH NIH U41** · RESEARCH TRIANGLE INSTITUTE · 2020 · $955,000

## Abstract

PROJECT SUMMARY/ABSTRACT
Biomedical science in the 21st century is a multidisciplinary and data-intensive enterprise that relies on clear
specification of research methods and results. The reproducibility of findings and the meta-analysis of pooled
data from disparate sources are both catalyzed by standard approaches to acquiring and representing data.
In this context, the PhenX (consensus measures for Phenotypes and eXposures) Toolkit
(https://www.phenxtoolkit.org/) is an increasingly valuable catalog of standard measures and bioinformatics
tools that help investigators improve the quality and consistency of data collection and identify opportunities
for collaborative research. Measures in the PhenX Toolkit are selected by working groups (WGs) of domain
experts using a consensus process and criteria established by the PhenX Steering Committee (SC). Since
its launch, PhenX has expanded beyond standard measures for genome-wide association studies (GWAS)
of common, complex diseases to include domains such as Rare Genetic Conditions, Sickle Cell Disease,
and Tobacco Regulatory Research.
The specific aims of the proposed Administrative Supplement “PhenX Measures for COVID-19” are as
follows: Specific Aim 1: Develop COVID-19 Core and Specialty collections. Specific Aim 2: Develop features
and tools for the COVID-19 page. Specific Aim 3: Establish PhenX measurement protocols for COVID-19
outcomes.
The crowd-sourcing approach defined here will rapidly establish COVID-19 Core and Specialty Collections
and raise awareness of the COVID-19 measurement protocols available in the PhenX Toolkit.Body Text (no
more than 30 lines)

## Key facts

- **NIH application ID:** 10179036
- **Project number:** 3U41HG007050-08S1
- **Recipient organization:** RESEARCH TRIANGLE INSTITUTE
- **Principal Investigator:** Carol Marie Hamilton
- **Activity code:** U41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $955,000
- **Award type:** 3
- **Project period:** 2013-07-01 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10179036

## Citation

> US National Institutes of Health, RePORTER application 10179036, Genomic Resource Grant for the PhenX Toolkit - expansion and sustainabilityPhenX Supplement for COVID-19 Research (3U41HG007050-08S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10179036. Licensed CC0.

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