# Signaling Pathways in Innate Immunity

> **NIH NIH T32** · UNIVERSITY OF MARYLAND BALTIMORE · 2021 · $420,232

## Abstract

An unprecedented expansion of knowledge in modern immunology has occurred in the relatively young field
of innate immunity. The “Signaling Pathways in Innate Immunity” (SPII) training grant (TG) program for pre-
and post-doctoral fellows is only in its 5th year of support and is thriving. The University of Maryland School of
Medicine (UMSOM) has significant research and training strengths in this area. The Training Grant Faculty
(TGF) for this unique, highly focused program are highly interactive and primarily drawn from the Department
of Microbiology and Immunology, with affiliations in interdisciplinary centers and institutes including the Center
for Vaccine Development, Institute for Genome Sciences, Center for Vascular and Inflammatory Diseases,
Greenebaum Cancer Center, and the Institute of Human Virology. The 28 TGF have a longstanding history of
collaboration on grants and publications, and are well funded PIs of grants totaling ~$13.1 million in annual
direct costs. Predoctoral trainees will be selected primarily from the interdepartmental Graduate Program in
Life Sciences (GPILS) Programs in Molecular Microbiology & Immunology (MMI), a well-established Ph.D.
Program that includes a rigorous core curriculum, program-specific courses, elective courses, journal clubs,
seminars, annual symposia, and graduate research presentation days. Additional academic work will be
combined with demanding laboratory training through dissertation research under the direction of the TGF
whose documented expertise will provide inter- and multidisciplinary training opportunities. Predoctoral
students are selected from an increasingly qualified applicant pool, as well as from the UMSOM M.D./Ph.D.
Program. Similarly, our TG-eligible postdoctoral trainees are increasingly gravitating to laboratories with
expertise in innate immune signaling where they receive dedicated mentoring, using state-of-the art resources.
Both pre- and postdoctoral trainees have additional didactic and non-didactic requirements, including training
in the responsible conduct of research, professional development, and a highly structured mentoring program.
Recruitment of trainees from underrepresented minorities is given significant priority through programs aimed
at facilitating success in our program, and is reflected in the diversity of our trainees: 13 of 20 training slots
(65%) went to women and 25% to underrepresented/disabled individuals. Our TG Program is guided by a
highly qualified Advisory Board including the Training Program Director, two Co-Directors, and individuals with
significant TG experience. Personal responsibility, including an insistence on scientific rigor and reproducibility,
and participation in scientific outreach programs, are strongly encouraged by our TGF using innovative new
training components. Our trainees are already building excellent records of publications and awards, and
several have already accepted research positions or have left for additional traini...

## Key facts

- **NIH application ID:** 10179301
- **Project number:** 5T32AI095190-10
- **Recipient organization:** UNIVERSITY OF MARYLAND BALTIMORE
- **Principal Investigator:** Stefanie N. Vogel
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $420,232
- **Award type:** 5
- **Project period:** 2012-06-15 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10179301

## Citation

> US National Institutes of Health, RePORTER application 10179301, Signaling Pathways in Innate Immunity (5T32AI095190-10). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10179301. Licensed CC0.

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