# Prevalence and Impact of Frailty among Dialysis Patients

> **NIH NIH K24** · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · 2021 · $149,045

## Abstract

PROJECT SUMMARY/ABSTRACT
I am applying to renew my Mid-career Investigator Award in Patient Oriented Research (K24) in order to
support my research and mentoring efforts. I am fully committed to patient oriented research and to training the
next generation of researchers in nephrology research. I have developed a research program studying physical
functioning in patients on dialysis, characterizing their limitations, studying the pathophysiology, and evaluating
interventions to improve functioning. While my previous and currently funded work aims to assess frailty and its
evolution among patients on dialysis, I am convinced that physical function and frailty could add important
information to inform clinical care at other points along the spectrum of CKD. In particular, I plan to expand my
focus to the transitions of care from non-dialysis requiring CKD to ESRD and from dialysis to transplantation.
Aims are to examine associations of functional status during CKD with outcomes during ESRD in a national
cohort of veterans and to measure physical performance in a cohort of kidney transplant candidates to
determine the extent to which post-transplant outcomes are related to physical performance and frailty during
pre-transplant evaluation. I have a strong track record of mentoring, and I work within a rich, supportive, and
collegial environment at UCSF and in the Division of Nephrology. Continued K24 funding will permit me to
continue to focus more of my time on research and mentoring and less on clinical and administrative work.

## Key facts

- **NIH application ID:** 10180945
- **Project number:** 5K24DK085153-11
- **Recipient organization:** HENNEPIN HEALTHCARE RESEARCH INSTITUTE
- **Principal Investigator:** KIRSTEN L. JOHANSEN
- **Activity code:** K24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $149,045
- **Award type:** 5
- **Project period:** 2018-12-18 → 2023-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10180945

## Citation

> US National Institutes of Health, RePORTER application 10180945, Prevalence and Impact of Frailty among Dialysis Patients (5K24DK085153-11). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10180945. Licensed CC0.

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