# Skeletal Phenotyping Core

> **NIH NIH P30** · MASSACHUSETTS GENERAL HOSPITAL · 2021 · $281,550

## Abstract

Identification of the structural, architectural, cellular and molecular basis for the skeletal phenotypes that result
from genetic/pharmacologic interventions and disease states is essential for translating scientific discoveries
into therapeutic innovations. The goal of the Skeletal Phenotyping Core is to provide cost-efficient, state of the
art, quality-controlled skeletal phenotyping services, continuing to fulfill the unmet needs of early stage
investigators who are transitioning to an independent career in skeletal biology, of established investigators
who are new to skeletal biology and of established skeletal biologists. Key missions of the Skeletal
Phenotyping Core include education, mentoring and incorporation of novel and innovative services to meet the
needs of the constituent investigators. Consultation regarding experimental design, specimen handling and
data analysis is provided by Core directors, to ensure that the maximal amount of data can be obtained from
each specimen/subject. The Core will conduct didactic teaching sessions, hands-on workshops and seminars
designed to educate investigators and to foster collaboration among investigators. A special focus of the Core
will continue to be mentorship of early stage investigators and of those investigators new to skeletal biology.
This infrastructure and these activities will continue to: 1) enhance the productivity and expand the scope of
research being conducted by the Core investigators, 2) promote innovation and incorporation of novel
technologies into core services, 3) foster synergy across a large and diverse community interested in skeletal
research, ultimately leading to levels of success greater than the sum of the individual investigators’ projected
achievements. These goals will be achieved by two specific aims: Aim 1) Provide efficient, high-quality, state-
of-the-art skeletal phenotyping services that are not readily supported by individual research grants in a timely
fashion; Aim 2) Provide training, and educational services to support new investigators in skeletal biology and
to facilitate collaboration among core investigators. In summary, the Skeletal Phenotyping Core will continue to
enhance the research productivity of a large and diverse community of investigators in skeletal biology by
ensuring accurate, efficient and comprehensive analyses of skeletal phenotypes.

## Key facts

- **NIH application ID:** 10183171
- **Project number:** 5P30AR075042-03
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** MARY L BOUXSEIN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $281,550
- **Award type:** 5
- **Project period:** 2019-06-19 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10183171

## Citation

> US National Institutes of Health, RePORTER application 10183171, Skeletal Phenotyping Core (5P30AR075042-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10183171. Licensed CC0.

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