# Patients Registry-Virtual Biorepository Core

> **NIH NIH U54** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2021 · $33,195

## Abstract

PROJECT SUMMARY
The Patient Registry and Biorepository has been designed to provide an optimal infrastructure for data
collection and archiving, data sharing, and biospecimen resource distribution in order to facilitate the
successful completion of the proposed Research projects as well as future Pilot and Cross-BETRNet Projects.
The database underlying the Columbia-UPenn-Mayo Patient Registry and Biorepository has been designed to
integrate seamlessly with the central system maintained at the BETRNet Coordinating Center and to maximize
ease of collaboration with other BETRNet Research Centers. The system has been designed to efficiently
transfer database to BETRNet Coordinating Center and to disseminate results among multiple venues. The
tissue repository is based on a large, long-standing tissue bank of surgical resections for esophageal cancer.
This Columbia-Mayo-Penn Patient Registry and Biorepository will serve as a unique resource for the three
projects that will be carried out during the proposed funding period, as well as for future projects related to
esophageal adenocarcinoma. The system has been designed specifically to achieve the following goals:
facilitating research related to the development of BE and its progression to EAC; translating these findings to
the patient-level with regards to biomarkers for risk stratification and chemoprevention; and ultimately reducing
the morbidity and mortality of EAC at a population level. The existing project website, which includes a link
allowing direct access to the BETRNet Coordinating Center, will be updated on a regular basis to include
postings of research results and provide access to published papers. A web-based Data Request form will
also be added to faciitate the delivery of data to investigators.

## Key facts

- **NIH application ID:** 10183181
- **Project number:** 5U54CA163004-10
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** HOWARD F. ANDREWS
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $33,195
- **Award type:** 5
- **Project period:** 2011-09-26 → 2024-10-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10183181

## Citation

> US National Institutes of Health, RePORTER application 10183181, Patients Registry-Virtual Biorepository Core (5U54CA163004-10). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10183181. Licensed CC0.

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