# A longitudinal investigation of minority stress in a diverse national sample of sexual minority adolescents

> **NIH NIH R01** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2021 · $731,475

## Abstract

PROJECT SUMMARY
The overarching goal of this study is to determine how different trajectories of minority stress experienced
throughout adolescence may predict behavioral health outcomes for SMA. Relying on methods established
and tested in our preliminary work, we will recruit a national sample of diverse SMA (e.g., race and ethnicity,
gender, urban vs. rural; N = 1,500) through both social media and respondent-driven sampling strategies in the
first year of the project. We will follow participants for three years, incorporating the fundamental tenets of
developmental psychopathology, which suggest that examining risk and protective factors for adolescents
necessitates longitudinal exploration across critical stages of development. Guiding the proposal are three
specific aims: Aim 1: Describe the individual and group trajectories of minority stress over time by following a
national sample of SMA (N = 1,500) for 3 years. WH1: There will be differences in minority stress across
adolescent development. Aim 2: Determine whether trajectories of minority stress are associated with
differences in behavioral health outcomes over time. WH2.1: Trajectories of minority stress and behavioral
health outcomes will be associated over time. WH2.2: Reporting higher levels of minority stress in early
adolescence will be associated with poorer behavioral health outcomes in later adolescence. Aim 3:
Determine whether the association between minority stress and behavioral health over time is different based
on sociodemographic characteristics (e.g., urbanicity, gender, race and ethnicity). WH3: There will be
significant differences in outcome trajectories by demographic subgroup. WH4: Trajectories of minority stress
will be inversely associated with protective factors over time and will differ by demographic subgroup. To test
our hypotheses, we propose cutting-edge longitudinal quantitative methodology including latent growth-curve
modeling, which are rarely used to examine longitudinal risk among SMAs. The proposed research will be the
first to determine how minority stress may influence health across adolescence, and this information can be
used directly to inform clinical assessment and the development of targeted behavioral health interventions for
this high-need population.

## Key facts

- **NIH application ID:** 10186558
- **Project number:** 5R01MD012252-05
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Jeremy Thomas Goldbach
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $731,475
- **Award type:** 5
- **Project period:** 2017-09-25 → 2022-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10186558

## Citation

> US National Institutes of Health, RePORTER application 10186558, A longitudinal investigation of minority stress in a diverse national sample of sexual minority adolescents (5R01MD012252-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10186558. Licensed CC0.

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