# Prenatal Social Connection and Disruption During the COVID-19 Pandemic: Effects on Maternal and Infant Health

> **NIH NIH R01** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2021 · $361,172

## Abstract

PROJECT SUMMARY
 The COVID-19 pandemic has had sweeping effects on pregnant women and their
partners. The need to adhere to social distancing guidelines has altered the social
connectedness of expectant parents, with effects on stress, loneliness, reduced access to in-
person prenatal care, and childbirth support. Social support during pregnancy is known to
buffer stress and predict better postpartum outcomes for both new parents and their infants.
For example, greater prenatal support has been linked with decreased risk of parental
postpartum mood and anxiety disorders, lower incidence of preterm birth and low birth
weight, calmer infant temperament, and healthier infant development. Given this evidence,
pandemic-induced changes to social connectedness during pregnancy may have long-term
effects for new parents and their children.
 The current proposal leverages the unique natural experiment of the COVID-19
pandemic to examine the maternal and infant health effects of social connectedness among
pregnant women and their partners. The CHIRP (Coronavirus, Health, Isolation and
Resilience in Pregnancy) study launched in spring 2020 and has enrolled 710 expectant
parents who reported on their feelings of social connectedness and support during
pregnancy. We will follow up with this cohort three, six, and 12 months after the birth of their
child. In addition to collecting self-report data, we will gather hospital birth charts to measure
gestational outcomes, and hair cortisol to measure neuroendocrine stress exposure. We also
plan to use geocoding to model the social, economic, and health impacts of the pandemic
and explore how these impacts shape postpartum outcomes. Our lab has already collected
data from another cohort of 200 expectant parents recruited during pregnancy and followed
over the transition to parenthood, constituting a pre-pandemic comparison sample with the
same measures and timing. We will also conduct a five-year follow-up with children from our
pre-pandemic dataset that will incorporate behavioral and neuroimaging measures of
neurodevelopment.
 Our pilot data indicates significantly higher ratings of psychological distress and lower
ratings of social support among expectant parents affected by the COVID-19 pandemic. We
expect that this project will make important contributions to the study of stress and resilience
during pregnancy and its long-term effects on both maternal and infant well-being.

## Key facts

- **NIH application ID:** 10187191
- **Project number:** 1R01HD104801-01
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Darby E. Saxbe
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $361,172
- **Award type:** 1
- **Project period:** 2021-06-01 → 2026-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10187191

## Citation

> US National Institutes of Health, RePORTER application 10187191, Prenatal Social Connection and Disruption During the COVID-19 Pandemic: Effects on Maternal and Infant Health (1R01HD104801-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10187191. Licensed CC0.

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