# Organ Specific Project - Kidney

> **NIH NIH U54** · VANDERBILT UNIVERSITY · 2020 · $1,269,052

## Abstract

Project Summary 
The goal of the Kidney OSP is to address the limitation in current knowledge of kidney biology by developing 
an ultra-high content mass spectrometry (MS)-based 3-dimensional (3-D) imaging pipeline to characterize the 
molecular signatures (lipids, metabolites and proteins) of different cell types and extracellular matrix 
components at high resolution in the intact human kidney. The imaging data acquired by this unique platform 
will be aligned and fused with the 3-D structure of the human kidney obtained by coordinate-based alignment 
with MRI, CT and histochemical based images. This technological pipeline will be developed to be compatible 
with other molecular interrogation pipelines generated through HuBMAP to create a comprehensive 
multidimensional 3-D molecular atlas of the normal human kidney.

## Key facts

- **NIH application ID:** 10187503
- **Project number:** 5U54DK120058-03
- **Recipient organization:** VANDERBILT UNIVERSITY
- **Principal Investigator:** RAYMOND C. HARRIS
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,269,052
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10187503

## Citation

> US National Institutes of Health, RePORTER application 10187503, Organ Specific Project - Kidney (5U54DK120058-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10187503. Licensed CC0.

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