# Integrative Health Sciences Facility Core

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2021 · $362,848

## Abstract

Project Summary of the Integrative Health Sciences Facility Core (IHSFC) 
The Integrative Health Sciences Facility Core (IHSFC) promotes the strategic goals of the Center for 
Environmental Health in Northern Manhattan (CEHNM) by supporting existing research projects and fostering 
new interdisciplinary research focusing on environmental health problems. In this competitive renewal, we 
propose to restructure the organization of CEHNM’s Facility Cores (FCs) to better serve Center members’ 
needs, increase efficiency, and enhance interdisciplinary research. The IHSFC is the central operational hub of 
this new structure. The IHSFC serves as the port of entry to all FC services and coordinates a highly effective 
pipeline of science that includes other two FCs, i.e., the Exposure Assessment FC (Exposure FC) and the 
Study Design and Data Analytics FC (Data FC). This structure supports members throughout all the stages of 
their research. CEHNM members receive support with conceptual input on design and study start-up at the 
front end, are supported throughout with a wide array of state-of-the-art analytical, technical, and study 
management services, and benefit from biostatistics, bioinformatics, and conceptual support to elevate their 
scientific output. The IHSFC directly contributes to this pipeline its long-standing expertise in collecting, 
managing, and supporting cutting-edge analysis on a wide array of biological samples. Specifically, it provides 
consulting services for biospecimen collection (including staff training in preparation for the study); prepares 
custom sample collection protocols; provides low-cost supplies for collecting urine, blood, and other samples, 
and then supports these collections with handling, pre-processing, and aliquoting. The IHSFC also supports 
CEHNM’s studies through biorepository management and provides access to existing biobanks for a large 
number of molecular epidemiology studies of environmental exposures and neurological, cardiovascular, and 
respiratory diseases, and cancer. The biorepository currently houses 375,000 individual aliquots from 133 
studies and provides prompt sample access and distribution. Finally, the lHSFC encompasses two laboratories 
that analyze biological samples: 1) the Biomarkers Lab that provides an extensive variety of analytical services 
that range from ELISA to library preparations for massive parallel sequencing; and 2) the Trace Metals 
Laboratory, which enables CEHNM members to precisely measure a broad range of metal biomarkers, 
including As, Pb, Se, Mn, Cd, Fe, and others, in urine, blood, hair, nail and other biological samples. Not only 
does the IHSFC deliver services to CEHNM members, including pro-bono or low-cost services for CEHNM 
pilot projects, but it also provides training for students, postdocs, fellows, junior faculty, and staff so that they 
can conduct the same type of work in their own labs, thus fostering career development and independence. 
Cons...

## Key facts

- **NIH application ID:** 10187572
- **Project number:** 5P30ES009089-23
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Regina M Santella
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $362,848
- **Award type:** 5
- **Project period:** 1998-07-01 → 2023-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10187572

## Citation

> US National Institutes of Health, RePORTER application 10187572, Integrative Health Sciences Facility Core (5P30ES009089-23). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10187572. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
