# Integrated Training in Reproductive Sciences

> **NIH NIH T32** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2021 · $193,008

## Abstract

This Training Program prepares physicians and scientists for investigative careers in reproductive
biology. During its 35 year history, the training grant has supported over 100 postdoctoral fellows who have
gone on to successful careers in academia and industry. The program is multifaceted and broadly based.
Research training is provided by 17 members of the Center for Reproductive Sciences (CRS) who hold faculty
positions in 8 departments. The Faculty have a broad range of scientific expertise and direct research
programs in reproductive biology, including: peimplantation embryo development and stem cell biology, germ
cell development, meiosis, follicular maturation, mechanisms of hormone action; molecular genetics, steroid
biosynthesis and action, endometrial and placental function, endocrine regulation of normal and abnormal
reproductive function, immune function in the maternal/fetal interface, basic and clinical studies of PCOS,
endometriosis, preeclampsia, and preterm birth. Technologies available include: human and mouse
embryology, embryonic and induced pluripotent stem cells, transgenic mice, Drosophila stem and germ cell
development, yeast models of meiosis, human genetics and genomics, state-of-the-art DNA and RNA
sequencing, protein/nucleic acid interaction technologies, single cell RNA sequencing, state-of-the-art
techonologies probing epigenetic marks and chromatin structure and non coding RNAs, microarrays and
proteomics, bioinformatics, mass spectrometric analysis of proteins and small molecules, cutting edge
microscopy and imaging technologies, in vitro fertilization, whole animal physiology, prospective clinical
investigation. Following formal application to the CRS, trainees are selected by an Admissions Committee.
Postdoctoral training will be offered to PhD fellows in related disciplines, and to clinically trained MD scientists
with prior specialty training. In addition to their research work, trainees take prescribed academic courses,
seminars, journal clubs, conferences, and seminars on the responsible conduct of research. Trainees learn to
design and execute basic and translational research projects, analyze data and write manuscripts for
prominent peer-reviewed journals. Trainees prepare and submit grant applications for extra-mural funding,
present seminars in reproductive biology, and learn how to mentor summer students working in the lab,
preparing them for independent academic careers. Trainee academic development is assured by mentoring
committees through individual development plans; success of trainees and the training program is tracked
through surveys of alumni. The strengths of the program include 1.) the diverse skills and interests of the
faculty, 2.) the interactiveness of the faculty 3.) our substantial laboratory and core facility resources 4.) the
outstanding environment for research in reproduction, development, endocrinology, cell biology, genetics and
related areas at UCSF and 5.) the commitment to the...

## Key facts

- **NIH application ID:** 10187601
- **Project number:** 5T32HD007263-38
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** SYNTHIA H MELLON
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $193,008
- **Award type:** 5
- **Project period:** 1983-07-01 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10187601

## Citation

> US National Institutes of Health, RePORTER application 10187601, Integrated Training in Reproductive Sciences (5T32HD007263-38). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10187601. Licensed CC0.

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