# UPSTATE KIDS ANALYSIS

> **NIH NIH N01** · UNIVERSITY OF MINNESOTA · 2020 · $119,392

## Abstract

The purpose of the Upstate KIDS Cardiovascular Disease (CVD) follow-up study is to determine if
infertility treatment is associated with a risk of CVD or the timing of puberty. Studies have shown
that some pubertal markers appear altered after IVF conception and early adrenarche may itself
confer a risk of CVD. Epigenetics may be the mechanism underlying treatment effects.
The Upstate KIDS study consisted of children conceived by infertility treatment and children
conceived naturally. In this follow-up study, specimens including blood and saliva were taken from
children between the ages of 6 and 8. Blood was also taken from mothers to assess confounding by
maternal CVD risk.

## Key facts

- **NIH application ID:** 10187717
- **Project number:** 275201800004I-0-759402000001-1
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** MICHAEL TSAI
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $119,392
- **Award type:** —
- **Project period:** 2020-07-01 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10187717

## Citation

> US National Institutes of Health, RePORTER application 10187717, UPSTATE KIDS ANALYSIS (275201800004I-0-759402000001-1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10187717. Licensed CC0.

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