# Studies on Antimicrobial resistance in bacteria of veterinary importance

> **NIH FDA U18** · NC STATE DEPT OF AGRI AND CONSUMER SERV · 2021 · $30,000

## Abstract

Project Summary
The North Carolina Veterinary Diagnostic Laboratory System is a full-service multidisciplinary veterinary
diagnostic laboratory. The NCVDLS received over 44,000 client accessions in 2018. Our diagnostic
laboratory is uniquely situated to screen for and research existing and emerging microbial pathogens of
agricultural and companion animal importance given the prominence of animal agriculture (poultry and swine
production) in our state and continual urban/suburban growth. The Bacteriology section services our main
laboratory and our three branch laboratories. Along with bacteriology submissions from clients they process
high volumes of in-house samples from necropsy. The bacteriology laboratory has MALDI-TOF and available
BSL3 workspace. The Bacteriology laboratory has performed over 13,900 tests in the year 2018 on clinical
samples, tissue, serum, bacterial isolates, and environmental samples. The NCVDLS hopes to partner with the
FDA and play an active role in pet food and animal feed contamination investigations:
 1) Participation in VPO designated sample analyses and surveillance activities to promote animal health
 and welfare and add to the Vet-LIRN Network's surge capacity to assist in emergency and large-scale
 outbreak testing.
 2) Provide analytical data to support regulatory actions by developing and using standardized methods,
 equipment platforms, and reporting methods, continued participation in proficiency testing provided by
 the VPO, continue investigating consumer reported cases as requested by the VPO, and continuing to
 improve and implement standardized quality management systems as designated by the VPO.
 3) Participate in small-scale antibiotic susceptibility testing studies by sharing bacterial isolates to address
 emerging antimicrobial resistance issues, and participate in AMR surveillance.
The bacteriology section of the NCVDLS hopes to engage in cooperative activities with the FDA Vet-LIRN, the
Vet-LIRN network, and federal, state, local and tribal organizations to promote animal health and feed and food
safety and security.

## Key facts

- **NIH application ID:** 10188545
- **Project number:** 5U18FD006672-03
- **Recipient organization:** NC STATE DEPT OF AGRI AND CONSUMER SERV
- **Principal Investigator:** James Trybus
- **Activity code:** U18 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2021
- **Award amount:** $30,000
- **Award type:** 5
- **Project period:** 2019-06-15 → 2023-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10188545

## Citation

> US National Institutes of Health, RePORTER application 10188545, Studies on Antimicrobial resistance in bacteria of veterinary importance (5U18FD006672-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10188545. Licensed CC0.

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