# Topical Therapies for Treatment of Cervical Intraepithelial Neoplasia 2-3

> **NIH NIH N01** · UNIVERSITY OF ARIZONA · 2020 · $225,296

## Abstract

Develop and conduct a phase 1 clinical trial to assess the safety and acceptability of once-weekly self-administered intravaginal application of 5-flurouracil (5-FU) and imiquimod used on alternating weeks for up to 16 weeks in women aged 18-45 years with biopsy confirmed high-grade cervical intraepithelial lesions.

## Key facts

- **NIH application ID:** 10189431
- **Project number:** 261201200031I-P00003-26100011-1
- **Recipient organization:** UNIVERSITY OF ARIZONA
- **Principal Investigator:** Sherry Chow
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $225,296
- **Award type:** —
- **Project period:** 2017-09-15 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10189431

## Citation

> US National Institutes of Health, RePORTER application 10189431, Topical Therapies for Treatment of Cervical Intraepithelial Neoplasia 2-3 (261201200031I-P00003-26100011-1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10189431. Licensed CC0.

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