# Administrative Core

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2021 · $932,129

## Abstract

ADMINISTRATIVE CORE (AC) : ABSTRACT
The Administrative Core (AC) of the Center of Excellence in Environmental Toxicology (CEET) is under the
effective leadership of two seasoned investigators with endowed chairs: Trevor Penning, PhD (Thelma Brown
and Henry Charles Molinoff Professor of Pharmacology) and Rebecca A. Simmons, MD (Hallam Hurt Endowed
Professor in Pediatrics). They ensure that the goals of the CEET strategic vision are achieved This vision
elevates the environmental health identity of the CEET at the institutional, regional, and national levels and
promotes team science within and across the CEET thematic areas. The AC guides the formation of flexible
thematic areas, which currently are in: Air Pollution & Lung Health, Environmental Exposures & Cancer,
Windows-of-Susceptibility, and Environmental Neuroscience. Investigators committed to these themes are led
by leaders of international repute in their respective areas. The AC provides oversight to the use of the Integrative
Health Sciences Facility Core (IHSFC), the Translational Biomarker Core (TBC) and the Exposure Biology
Informatics Core (EBIC) to ensure they address the needs of the thematic areas and the CEET investigator. The
AC encourages communication, interaction, involvement and exchange with the Community Engagement Core
(CEC) to bring community concerns to the attention of thematic area investigators and the IHSFC. Evaluation
and guidance in decision making processes is overseen by four committees, the Internal Advisory Committee,
the Executive Committee, the Directors Council and the External Advisory Board. Reporting and fiscal
management are supported by an experienced Center Administrator and Grants Manager. A central component
of the AC is to cultivate the careers of Early-Stage Investigators (ESI) to establish them as the next generation
of environmental health (EH) scientists. Our philosophy is that environmental health science is unique among
the biomedical sciences since it spans diverse interdisciplinary expertise ranging from mechanistic toxicology,
epidemiology, exposure science, and translation to patients, communities, and policy makers. In addition,
successful EH scientists are increasingly faced with “Big-Data”, and how to transform such data into knowledge
which requires familiarity with bioinformatics tools and the advances being made in computational science,
machine learning and AI. Our Environmental Health Scientist Support Program is designed to provide a
transformative experience so that our ESI will be equipped with the tools for success as the next generation of
EHS scientists. The AC also builds capacity by bringing senior investigators into the CEET who are addressing
environmental health problems for the first time in their careers. In this manner the AC is responsive to the NIEHS
strategic plan which stresses stewardship of resources and building the professional pipeline.

## Key facts

- **NIH application ID:** 10189587
- **Project number:** 5P30ES013508-16
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Trevor M Penning
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $932,129
- **Award type:** 5
- **Project period:** 2006-04-01 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10189587

## Citation

> US National Institutes of Health, RePORTER application 10189587, Administrative Core (5P30ES013508-16). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10189587. Licensed CC0.

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