# Integrative Health Sciences Facility Core

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2021 · $353,242

## Abstract

INTEGRATIVE HEALTH SCIENCES FACILITY CORE (IHSFC): ABSTRACT 
The IHSFC is the entity that enables CEET investigators to perform translational environmental health research 
that impacts individuals and communities. Its mission includes (1) support of the translation of basic science 
observations that relate environmental exposures to adverse outcomes into human studies that detect, prevent 
and/or manage diseases induced or exacerbated by these exposures and (2) to translate EHS questions derived 
from the community into testable hypotheses that can be addressed with human studies. Services provided by 
the IHSFC to CEET investigators include: (a) Human Studies Design and Performance Services, (b) Population 
Exposure Services, (c) Pre-clinical and Human Exposure Laboratories, (d) the CEET Virtual Biorepository and 
(e) Biostatistics Services. The Population Exposure Services now has expertise in GIS technology, ArcGIS 
tools, cartographic mapping, geospatial analysis to measure the external exposome. Population science-based 
projects that require biomarker support in the study design are referred to the Translational Biomarker Core, and 
those that generate “big-data” in their study design are referred to the Exposure Biology Informatics Core. The 
IHSFC acts as a bridge to the Community Engagement Core (CEC) and communicates in a bi-directional manner 
to formulate community-based questions and concerns into specific hypotheses for CEET investigators to 
address by research and communicate results of the studies back to community members. Studies supported 
by the IHSFC include those involving the integrated thematic areas of Air Pollution & Lung Health, Environmental 
Exposures & Cancer, Windows-of-Susceptibility and Environmental Neuroscience, as well as novel studies 
initiated via pilot projects. Over the past four years, the IHSFC has supported 51 separate studies involving 28 
different CEET investigators that have generated 46 publications. Efforts by the IHSFC will ultimately result in 
achieving Precision Public Health (PPH) - the prediction of who is at risk of exposure, who is at risk for disease, 
and the identification of predictive and prognostic biomarkers.

## Key facts

- **NIH application ID:** 10189588
- **Project number:** 5P30ES013508-16
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Anil Vachani
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $353,242
- **Award type:** 5
- **Project period:** 2006-04-01 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10189588

## Citation

> US National Institutes of Health, RePORTER application 10189588, Integrative Health Sciences Facility Core (5P30ES013508-16). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10189588. Licensed CC0.

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