# Training in Integrative and Systems Biology of Cardiovascular Disease

> **NIH NIH T32** · WASHINGTON UNIVERSITY · 2021 · $324,624

## Abstract

This proposal seeks support for the Training in Integrative and Systems Biology of Cardiovascular
Disease Training Program in the Center for Cardiovascular Research at Washington University. The goals of
this Program are to provide predoctoral and postdoctoral trainees with: outstanding research opportunities;
fundamental education and basic training in cardiovascular physiology, pathophysiology and disease
mechanisms; opportunities to be introduced to, and potentially to participate in, translational cardiovascular
research; and, mentoring to prepare them to be productive, independent scientists, educators and mentors.
The critical components and the clear strengths of this Program are the twenty-one (21) participating faculty
and the trainees themselves. Another clear strength of this Training Program is the highly interactive and
collaborative environment in the Center for Cardiovascular Research, indeed at Washington University in
general, which translates to expanded research, education, training and mentoring opportunities for all of our
trainees. The participating training faculty derive from seven Departments and four Divisions within the
Department of Internal Medicine, and includes nationally and internationally recognized leaders in the three
research and training areas of emphasis in this Training Program: 1) Cardiac metabolism, remodeling and
cardiomyopathies; 2) Ion channels, cardiac excitability and arrhythmias; and, 3) Vascular biology, inflammation
and coronary disease. The participating faculty are all well-funded, highly interactive, collaborative and
productive investigators who are all also committed to providing the training, experience, resources, intellectual
enthusiasm, and mentoring needed to facilitate the scientific and professional development of the Program
trainees. Importantly, the more experienced senior faculty participants are also committed to the mentoring of
the more junior Training Program faculty preceptors. In addition to the research training provided in individual
and collaborating laboratories, trainees in this Program will also participate in a “Core Curriculum in Integrative
and Systems Cardiovascular Biology”, the weekly "Trainees in Cardiovascular Biology" and “Cardiovascular
Research” seminar series, the biannual “Cardiovascular Training Program Distinguished Lectureship,” the
annual “Cardiovascular Research Day”, and have the opportunity to participate in translational cardiovascular
research. This Training Program also provides trainees with continuing instruction in Ethics and Research
Science, and has outlined formal and informal mechanisms for helping trainees develop individualized
educational, training and career development plans and for monitoring the progress, professional development
and mentoring of each predoctoral and postdoctoral trainee. Formal mechanisms are also in place for
evaluating, and evolving as needed, the Training Program itself going forward.

## Key facts

- **NIH application ID:** 10189686
- **Project number:** 5T32HL134635-05
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** JEANNE M. NERBONNE
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $324,624
- **Award type:** 5
- **Project period:** 2017-07-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10189686

## Citation

> US National Institutes of Health, RePORTER application 10189686, Training in Integrative and Systems Biology of Cardiovascular Disease (5T32HL134635-05). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10189686. Licensed CC0.

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