# Clinical Pharmacology Training Program

> **NIH NIH T32** · VANDERBILT UNIVERSITY MEDICAL CENTER · 2021 · $611,296

## Abstract

The discipline of Clinical Pharmacology seeks to apply an understanding of the fundamental mechanisms of
drug action to improve the therapy of human diseases. The Division of Clinical Pharmacology at Vanderbilt
offers an outstanding research-based, postgraduate fellowship program committed to training future leaders in
the discipline. The mentoring faculty includes 20 members of the Division of Clinical Pharmacology, along with
20 members of other divisions or departments. Collaborations among investigators focusing on common
research themes are well-established in the Division; areas of research focus include 1) Drug
metabolism/Pharmacogenetics/Personalized Medicine; 2) Eicosanoid and lipid mediator pharmacology; 3)
Vascular biology and control of the circulation; 4) Ion channel pharmacology and arrhythmia
pharmacogenomics; 5) Bone and cancer pharmacology; and 6) Pharmacoepidemiology. Additional
collaborative efforts exist in pediatrics, cardiology, rheumatology, bioinformatics, genetics and
neuropharmacology among others. The primary activity of trainees is research training in a mentored setting
on questions directly relevant to drug action in man. Research can vary from bench-based translational work to
clinical studies. There are currently 7 postdoctoral fellows (5 MDs and 2 MD, PhDs) supported by this grant.
The duration of training is 2-3 years and individuals holding either an M.D., Ph.D., or Pharm.D. degree are
supported. Research training under the direction of individual faculty mentors is supplemented by didactic
course work and seminars. Required courses of trainees include research ethics, responsible conduct of
research, biostatistics and study design, drug regulation and development, and pharmacokinetics and
pharmacodynamics. In addition, attendance at Clinical Pharmacology Grand Rounds and a weekly Fellows'
Lecture Series is required. This curriculum supplements the trainees' research experience and provides a
broad knowledge base that will allow for fellows to develop into successful leaders in Clinical Pharmacology.
The excellence of the training program has resulted in substantially more applicants than positions. Growth of
clinical pharmacology at Vanderbilt offers unique opportunities to further enhance the training program. Such
growth includes the Oates Institute of Experimental Therapeutics that focuses on pharmacogenetics and
personalized medicine; the Vanderbilt Center for Bone Biology; and the recently established Vanderbilt Center
for Arrhythmia Research and Therapeutics (VanCART) - all components of the Division of Clinical
Pharmacology. The overall mission of the Vanderbilt Clinical Pharmacology program is to train investigators
who will ultimately assume leadership positions in the discipline and it has been highly successful in that
mission. Of trainees supported by the award in the past 10 years approximately 90% are in academic
medicine, industry, or government. Clinical Pharmacology at Vanderbilt is a vibrant a...

## Key facts

- **NIH application ID:** 10192730
- **Project number:** 5T32GM007569-46
- **Recipient organization:** VANDERBILT UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** Bjorn C Knollmann
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $611,296
- **Award type:** 5
- **Project period:** 1977-07-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10192730

## Citation

> US National Institutes of Health, RePORTER application 10192730, Clinical Pharmacology Training Program (5T32GM007569-46). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10192730. Licensed CC0.

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