# Endocrinology and Metabolism Training Program

> **NIH NIH T32** · DUKE UNIVERSITY · 2021 · $316,589

## Abstract

Project Summary/Abstract
The Endocrinology and Metabolism Research Training Program (T32) at Duke University Medical Center is
centered on clinical and basic science investigators in the Division of Endocrinology, as well as collaborators
working in other divisions and departments. The broad goal of this program is to train the next generation of
biomedical scientists working in Diabetes, Metabolism and related diseases. Post-doctoral participants in this
program will be either board- eligible or board-certified physicians with training in Internal Medicine or
Pediatrics, or PhD scientists pursuing careers in endocrine/metabolic research.
The Duke Endocrinology T32 has a long track record of training successful investigators in diabetes,
metabolic bone disease, and other areas of endocrine/metabolic research. A substantial majority (80% of
trainees over the past two cycles of the grant) are in academic positions at major medical centers across
the US and abroad. Most are in positions with substantial research components, supported by federal,
foundation, or industry grants, and the remainder have significant teaching responsibilities.
The program includes training opportunities in clinical, translational, and basic research. Mentors associated
with this grant have funded research programs ranging from basic science (islet biology, mitochondrial
function and energetics, metabolic flux, transcriptional regulation of metabolism), to preclinical physiology
using mouse genetic models, clinical physiology in humans (insulin secretion, incretin function, exercise and
metabolism, bariatric surgery) to implementation science (novel approaches to diabetes care and weight
management), and outcomes research (clinical trials and epidemiology). Trainees will choose primary
mentors, but have access to the full breadth of the mentorship team through collaborations, didactic teaching
and seminars. Training is aimed at identifying important research questions, formulating incisive hypotheses
and learning to design simple but dispositive experiments; technical and analytic proficiency will also be
stressed. Individuals who complete the program will be capable of independent investigation and able to
translate research accomplishments into significant advances with clinical relevance.

## Key facts

- **NIH application ID:** 10197103
- **Project number:** 5T32DK007012-43
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** DAVID A. D'ALESSIO
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $316,589
- **Award type:** 5
- **Project period:** 1975-07-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10197103

## Citation

> US National Institutes of Health, RePORTER application 10197103, Endocrinology and Metabolism Training Program (5T32DK007012-43). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10197103. Licensed CC0.

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