# Lesion Analysis/Biostatistics Core

> **NIH NIH P01** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2021 · $322,748

## Abstract

Core A – Project Summary/Abstract
 The Lesion Analysis/ Biostatistics Core will continue to provide support to each of the three
projects in study design and assessment of atherosclerotic lesion development. The Core
ensures consistent quantitative and qualitative assessment of atherosclerotic lesions,
adequately powered experimental design and appropriate analysis of experimental results
across all three projects of the PPG. Specifically, the Core will provide state-of-the-art expertise
in A) quantification of atherosclerotic lesions; B) qualitative assessment of lesion composition;
C) apoptosis and in situ efferocytosis assays; D) markers of cell adhesion and inflammation; E)
laser-capture microdissection (LCM) for cell-specific quantitative gene expression analyses; and
F) biostatistical support including study design and power analyses. In addition, the Core will
provide biostatistical support for genome-wide transcriptomic and chromatin analyses via the
expertise of Dr. Ying Wei, Professor of Biostatistics.

## Key facts

- **NIH application ID:** 10197187
- **Project number:** 5P01HL087123-14
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** NAN WANG
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $322,748
- **Award type:** 5
- **Project period:** 2007-07-15 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10197187

## Citation

> US National Institutes of Health, RePORTER application 10197187, Lesion Analysis/Biostatistics Core (5P01HL087123-14). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10197187. Licensed CC0.

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