# Diabetes Genomics and Analysis Core

> **NIH NIH P30** · STANFORD UNIVERSITY · 2021 · $211,911

## Abstract

Project Summary / Abstract (DGA Core)
The Stanford Diabetes Genomics and Analysis (DGA) Core is designed to support the genomic research of
Stanford Diabetes Research Center (SDRC) investigators through access to next-generation sequencing and
modern bioinformatics analysis. Nucleotide sequencing has become essential for formulating and resolving
crucial biological questions in many contexts, like diabetes. This includes determining the underlying causes of
human diseases to monitoring gene expression, elucidating regulatory networks and exploring organismal
diversity that may impact human health, like human microbiomes. Thus, high-throughput sequencers have
become a transformative tool for a wide variety of studies in both pure and applied biomedical science.
Researchers use this technology increasingly for an ever-broadening range of applications to detect and
characterize nucleic acid molecules (RNA and DNA). The overall goal of the Stanford DGA Core is to provide
SDRC investigators with a next-generation sequencing facility composed of state-of-the-art laboratory,
computational facilities and informatics support.
The DGA Core is committed to providing SDRC laboratories with the expertise and technical support
necessary to realize the potential of next-generation sequencing in a cost-effective matter regardless of their
existing expertise in genomics. The Stanford DGA Core will offer a complete package of services ranging from
study design consultation, library preparation services, access to sequencing technologies, and analysis and
interpretation of sequencing data. SDRC laboratories can leverage the technologies and expertise of the
Stanford DGA Core to overcome cost-prohibitive barriers of entry into genomics which include technologically
advanced facilities and equipment, and computational infrastructure that can only be achieved in a center
setting like the Stanford DGA Core. Based on the strengths of the Stanford DGA Core and its contributions, the
specific aims of the DGA Core are to provide SDR core users guidance with design of their next-generation
sequencing projects, access to a broad range of nucleotide library preparation services, access to sequencing
services with modern sequencing technologies, and support with data analysis and interpretation of their
sequencing projects
The proven strengths of the Stanford DGA Core in these techniques will provide investigators with a unique
opportunity to effectively apply powerful research approaches that would be prohibitively difficult for individual
laboratories to develop. The Stanford DGA Core will serve as an invaluable resource for the SDRC, providing
investigators with the next-generation sequencing expertise and training necessary to examine the genome at
a level that is limited to a relatively few laboratories. This Core is committed to serving SDRC investigators in
their experiments, from start to finish.

## Key facts

- **NIH application ID:** 10197907
- **Project number:** 5P30DK116074-05
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** HASSAN CHAIB
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $211,911
- **Award type:** 5
- **Project period:** 2017-09-15 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10197907

## Citation

> US National Institutes of Health, RePORTER application 10197907, Diabetes Genomics and Analysis Core (5P30DK116074-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10197907. Licensed CC0.

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