# Core-005

> **NIH NIH UL1** · OREGON HEALTH & SCIENCE UNIVERSITY · 2021 · $1,645,025

## Abstract

OHSU has a robust research portfolio in child health, older populations, diseases across the lifespan, and
underserved rural populations. However, there are significant gaps in coordinated support for these
important programs that impair optimal performance and expansion of these efforts. The new OCTRI
Integrating Special Populations unit (ISP) will enhance research in child health, older populations, diseases
across the lifespan, and underserved rural populations with a critical analysis of current needs, development
of feasible goals to address these needs, implementation of the highest priority goals, and evaluation and
dissemination of the most effective processes. Planned activities include regional conferences and retreats
with investigators and other stakeholders, development of toolkits and other educational modules, enhanced
informatics tools, and other techniques tailored to each program. The ISP will coordinate closely with the
CTSA network to adopt effective techniques developed at other CTSA sites, and to share local proven
techniques after careful evaluation. These efforts will enhance knowledge of health-related issues in these
special populations, leading to improved interventions to optimize their health and well-being.
The OCTRI Clinical and Translational Research Center (CTRC) has greatly expanded and enhanced the
conduct of clinical research at OHSU, with unprecedented growth over the past five years. The CTRC also
serves as a major site for career development in clinical research at OHSU. However, stressors on CTRC
operational and financial structures require a new funding model and increased operational efficiencies.
These accomplishments and challenges set the stage for continued evolution of OCTRI’s Participant and
Clinical Interactions (PCI) research capacity for the next five years. The CTRC will catalyze scientifically
rigorous, ethical, feasible, and efficient patient-oriented research studies, with an emphasis on intensive
phenotyping and early phase clinical trials in high priority areas for OHSU investigators. These efforts will
advance knowledge of numerous human diseases and lay the foundations for disease-specific therapeutics
to enhance human health. The CTRC will also continue to leverage and enhance the OCTRI Educational
Program by utilizing the CTRC as the mentored “laboratory” for students, investigators, and study staff
pursuing patient- oriented research. Finally, the CTRC will complete its transition to a new operational
model as a University Shared Resource (USR), incorporating continuous quality improvement to ensure
that sustainable and efficient operational and financial processes are in place to optimally support PCI
research at OHSU and the region.

## Key facts

- **NIH application ID:** 10198074
- **Project number:** 5UL1TR002369-05
- **Recipient organization:** OREGON HEALTH & SCIENCE UNIVERSITY
- **Principal Investigator:** David Hoadley Ellison
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,645,025
- **Award type:** 5
- **Project period:** 2017-09-02 → 2022-08-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10198074

## Citation

> US National Institutes of Health, RePORTER application 10198074, Core-005 (5UL1TR002369-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10198074. Licensed CC0.

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