# Training in Transplantation Biology

> **NIH NIH T32** · MASSACHUSETTS GENERAL HOSPITAL · 2021 · $306,384

## Abstract

PROJECT SUMMARY/ABSTRACT
Transplantation is an exciting field of clinical medicine with great potential for alleviating human disease.
Because clinical transplantation is intimately associated with basic and translational scientists at
Massachusetts General Hospital (MGH)/Harvard Medical School (HMS) in immunology and related disciplines,
this field provides tremendous opportunities for training of scientists. MGH and HMS have outstanding teams
of M.D. and Ph.D. scientists devoted to all aspects of transplantation, from the most basic molecular level to
clinical transplantation, providing a unique environment to foster such training at the interface of clinical care
and basic science. The purpose of our Program is to train young scientists and physician-scientists in basic
and translational research, in the diverse lines of investigation related to transplantation biology, in this multi-
disciplinary environment, with emphases on immunological mechanisms with translational applications.
Participating faculty members with diverse but complementary research interests, a successful record of
collaboration, and a commitment to training young investigators, have been assembled to provide trainees with
exposure to topics related to transplantation immunobiology including immunogenetics, tolerance induction,
antigen processing and presentation, bone marrow transplantation, regulation of lymphocyte development,
pathology of graft rejection, complement biology, autoimmune disease, dendritic cell biology, chemokines and
lymphocyte trafficking, B and T cell biology, regulatory T cells, mucosal immunology, gene editing, infection,
cancer biology, and xenotransplantation. The major goal of this program is to develop outstanding
independent investigators capable of addressing fundamental questions in the field of transplantation
and the application of this knowledge to important clinical challenges. Pre-doctoral trainees will be
selected from students currently enrolled in the Immunology Program at Harvard University's Division of
Medical Sciences with an interest in pursuing thesis research in the field of transplantation immunology.
Training for pre-doctoral students takes approximately 5 years, and students commit to thesis laboratories in
the second year of graduate school. Pre-doctoral trainees already in transplantation-related research
laboratories and distributed between students in their 3rd, 4th or 5th year of thesis research will be selected.
Post-doctoral trainees currently holding a degree of MD, PhD, or MD/PhD will be selected with outstanding
potential for careers in research and teaching and a commitment to independent investigation. Training will
require 2-3 years. This program builds on our unique and dynamic environment to optimize individual training
and mentorship experiences, by expanding into new areas of research, by recruitment of trainees and faculty
from groups underrepresented in transplant research, to advance excellence in the fie...

## Key facts

- **NIH application ID:** 10198707
- **Project number:** 5T32AI007529-22
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** Joren C Madsen
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $306,384
- **Award type:** 5
- **Project period:** 1998-09-01 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10198707

## Citation

> US National Institutes of Health, RePORTER application 10198707, Training in Transplantation Biology (5T32AI007529-22). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10198707. Licensed CC0.

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