# NRSA Training Core

> **NIH NIH TL1** · MAYO CLINIC ROCHESTER · 2021 · $495,189

## Abstract

A new generation of researchers is needed who can participate in and lead multidisciplinary teams that
understand the process of translation from discovery to application to improvements in health. The long-term
objective of TL1-supported programs within the Mayo Clinic Center for Clinical and Translational Science
(CCaTS) is to train tomorrow's workforce of team-based, translational biomedical researchers at predoctoral
levels. Three Specific Aims are proposed: 1) Recruit a diverse group of students at multiple career levels
and integrate learning across these learner groups through a variety of programs. 2) Implement learning
strategies for these students using novel curricula based on the R4 approach (the Right education at the
Right time to the Right learner with the Right method), using novel approaches including case-based learning;
team-based learning; task-oriented learning; and immersion in internships within industry, regulatory agencies,
start-ups, and organizations that succeed through teamwork. 3) Rigorously evaluate outcomes and
disseminate successful models, so that these novel programs can be continuously improved and the CTSA
Consortium and others can benefit from these experiences.
Ten slots are requested to support 3 different experiences: 1) The PhD Program in Clinical and Translational
Science, an innovative PhD track developed de novo to accelerate the education of leaders in translational
team research; 2) the Master's Degree in Clinical and Translational Science for medical students to prepare
future physicians for careers in clinical and translational science; 3) short-term medical school research
experiences to introduce students to the clinical and translational research process, and to motivate them to
pursue further research training. An extensive framework for the TL1 Core that emphasizes diversity has been
successfully built over the last 9 years. We will build upon this considerable experience, retaining those
elements of proven benefit and implementing enhancements in the next funding cycle. Highlights of these
enhancements include expanded training opportunities in team science, entrepreneurship, and the science of
Translation and Regulatory Science; expanded opportunities for experiential learning on the Mayo campus, in
partner institutions, and in novel extramural environments; enhanced ability to tailor didactic curricula to
individual needs; and increased leveraging of institutional strengths in growth areas within the institution.
Established collaborations with partner institutions, including the University of Minnesota CTSI and the
University of Puerto Rico, will be strengthened, and rigorous evaluation systems that use innovative and
comprehensive metrics to track individual and program progress and outcomes will be developed further.
Successful practices will be disseminated through CTSA networks and national leadership.

## Key facts

- **NIH application ID:** 10199783
- **Project number:** 5TL1TR002380-05
- **Recipient organization:** MAYO CLINIC ROCHESTER
- **Principal Investigator:** ANTHONY John WINDEBANK
- **Activity code:** TL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $495,189
- **Award type:** 5
- **Project period:** 2017-09-18 → 2022-07-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10199783

## Citation

> US National Institutes of Health, RePORTER application 10199783, NRSA Training Core (5TL1TR002380-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10199783. Licensed CC0.

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