# Training Program in the Genetic Basis of Pediatric Gastrointestinal Disorders

> **NIH NIH T32** · CHILDREN'S HOSP OF PHILADELPHIA · 2021 · $234,187

## Abstract

PROJECT SUMMARY/ABSTRACT
Training  in  the  genetic  basis  of  pediatric  gastrointestinal  disorders:  The  revolutions  in  genetics  and 
genomics  have  led  to  discoveries  in  a  range  of  GI  diseases,  many  of  which  affect  the  health  of  children.  
Pediatric gastroenterologists who are trained in genetic research will be essential in the effort to identify novel 
genetic  causes  of  GI  disease,  reveal  their  molecular  mechanisms,  and  translate  them  into  therapy.  The 
outstanding  laboratory,  translational,  and  clinical  research  at  CHOP  and  the  Perelman  School  of  Medicine 
(PSOM) present an ideal environment for research career development in the genetics of pediatric GI disease. 
The overarching goals of this training program are to:  
• Train a cadre of committed researchers to investigate the genetic basis of pediatric GI disease and to use 
this knowledge to improve the health of children and adults.  
• Provide these individuals with the skill sets and foundation for career advancement.  
• Encourage innovation and leadership in academic pediatric GI. 
The Specific Aims of this training program are to: 
 • Identify,  recruit  and  foster  the  career  development  of  post-­doctoral  research  trainees  from  the  pool  of 
CHOP GI fellows, PSOM GI fellows, and other scientists committed to training and career development in 
the genetics of pediatric gastrointestinal disease.  
• Match trainee strengths and interests with mentoring teams.  
• Provide intensive mentored research experience and training with dedicated faculty.  
• Provide career mentoring, including training on successful grant and manuscript preparation.  
 • Bring  together  faculty  and  fellows  through  seminar  series  and  other  academic  activities  to  create  a 
collaborative community of physician-­scientists. 
 • Provide  guidance  for  structured  learning  opportunities  on  the  principles  of  genetic  research,  including 
research ethics and the protection of animal and human subjects.  
To  achieve  these  goals,  we  have  designed  a  program  offering  mentored  independent  research  with  a  team 
approach  and  scholarship  oversight.  The  program  provides  career  mentorship,  including  individualized 
independent  development  plans  (IDP)  and  workshops  focusing  on  professional  development  and  career 
advancement skills.  Seminars are focused on cutting edge research and progress in the field. In the first cycle 
of  funding,  we  have  trained  6  outstanding  fellows,  4  of  whom  have  graduated  and  are  pursuing  successful 
academic careers, 3 with additional funding.  Our goal over the next 5 years is to build upon this foundation to 
continuously  improve  our  training  program  with  innovative  opportunities,  and  continue  our  mission  of  training 
the next generation of physician scientists to investigate the complex genetics of GI disorders.

## Key facts

- **NIH application ID:** 10200024
- **Project number:** 5T32DK101371-08
- **Recipient organization:** CHILDREN'S HOSP OF PHILADELPHIA
- **Principal Investigator:** Kathleen Mary Loomes
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $234,187
- **Award type:** 5
- **Project period:** 2014-07-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10200024

## Citation

> US National Institutes of Health, RePORTER application 10200024, Training Program in the Genetic Basis of Pediatric Gastrointestinal Disorders (5T32DK101371-08). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10200024. Licensed CC0.

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